Despite a number of respiratory syncytial virus (RSV) vaccine candidates being tested in clinical trials, disease-specific, self-reported instruments assessing symptom severity of RSV infection from the perspective of adult patients are still needed. The RSV Infection, Intensity and Impact Questionnaire ...
The percentage of people who would recommend an FDA-approved RSV vaccine to pregnant people and adults 65 and older. Credit: Annenberg Public Policy Center’s ASAPH survey June 2023 By the age of 2, nearly all children get sick from RSV, which was one of three illnesses – with the flu...
Fewer infants in the nonadjuvanted vaccine arm experienced nonsevere RSV-LRTI, but this end point did not meet prespecified success criteria. The nonadjuvanted vaccine AEs were generally mild to moderate, with injection site pain being the most common. Adjuvanted, Preservative-Free RSV Vaccine In ...
Ideally, the choice of whether a pregnant person should get the vaccine or wait to give their baby the antibodies after birth should be up to the pregnant person. But this year, Hughes said, getting what you know is available may make the most sense. In some ways, it’s reminiscent of...
Methods We conducted a systematic literature search to identify full-text articles published from 2003 to 2023 and reporting data on the epidemiological or economic burden of RSV in Germany. Based on pre-specified eligibility criteria, data on incidence, rates of ...
Pfizer's clinical trialresultsfound 69.4% vaccine efficacy in lowering the risk of severe lower respiratory tract illness, through six months after birth. That was well above the minimum criteria to be licensed, the FDA said, though they noted protection against infection is expected to wane as ...
However, while some vaccine candidates against RSV and influenza may have the capacity to induce CD8+ T cells, they have not yet been shown clinically to improve protection3,4,5. RSV is globally the commonest cause of lower respiratory tract infection in children, leading to an estimated 3.4...
"Breastfeeding clearly decreases the baby's chance of having to have an outpatient visit or go to the hospital or worse, go to the intensive care unit," Dr. Paul Offit, director of the vaccine education center and pediatrician in the division of infectious diseases at Children's Hos...
Similar inclusion/exclusion criteria and RT-PCR diagnosis were used for both studies, with addition of serology only in the first. All cases were adjudicated for bacterial coinfection and radiographic pneumonia by 1 pulmonary and 3 ID physicians. Comparisons used t-test or 蠂2.Table 2.Signs and...
The main difference for parents to note between the two vaccines is that an infant needs to meet specific criteria to qualify for a prescription for the Synagis vaccine. These criteria, such as being born very prematurely (less than 29 weeks) or having heart or lung disease or a problem wit...