（antibody-dependent enhancement， ADE）。不过RSV的灭活疫苗引发的还不是ADE，而是疾病增强作用（Enhanced...
ANTIBODY MEDIATED ENHANCEMENT (AME) OF RESPIRATORY SYNCYTIAL VIRUS (RSV) INFECTION IN A MACROPHAGE-LIKE CELL LINE (P388D1)doi:10.1203/00006450-198704010-00966RSV bronchiolitis occurs in infants 4 PFU/ml vs 1.9×103 for RSV only; anti-G at 1:400=2.2×103 PFU/ml vs 2.1×102 for RSV only...
ARTICLES OPEN Airway T cells protect against RSV infection in the absence of antibody E Kinnear1, L Lambert1, JU McDonald1, HM Cheeseman1, LJ Caproni2 and JS Tregoning1 Tissue resident memory T (Trm) cells act as sentinels and early responders to infection. Respiratory syncytial virus (RSV...
RSV）是世界范围内引起5岁以下儿童急性下呼吸道感染（如毛细支气管炎、肺炎等）最重要的病毒病原。
infection with wild-type RSV protects against subsequent exposures17 and antibody has a role in this protection, but the role of T cells is unclear. The aim of the study was to investigate the role of lung-resident T cells in protection against RSV infection. The response to RSV was ...
Porterfield JS (1986) Antibody-dependent enhancement of viral infectivity. Adv Virus Res 31:335–355 Article PubMed CAS Google Scholar Prince GA, Hemming VG, Horswood CL, Chanock RM (1985a) Immunoprophylaxis and immunotherapy of respiratory syncytial virus infection in the cotton rat. Virus Res...
大多数严重感染发生在年幼的婴儿身上，下呼吸道疾病 (LRTI) 的发病率高峰出现在 2 至 4 个月大之间...
FIG. 2 shows the antibody titers in the same experiment as described above. Both vectors induced very clear time and dose-dependent increase in ELISA titers (FIG. 2). Anti-F titers clearly increase from 2 to 8 weeks, which was significant for the 1010dose. At 8 weeks there was no diffe...
ANTIBODY MEDIATED ENHANCEMENT (AME) OF RESPIRATORY SYNCYTIAL VIRUS (RSV) INFECTION IN A MACROPHAGE-LIKE CELL LINE (P388D1)Pediatric Research publishes original papers, invited reviews, and commentaries on the etiologies of diseases of children and disorders of development, extending from molecular ...
The 60% plaque reduction neutralizing antibody titers (PRNT60) were determined as described previously. Statistical differences compared with wt rRSV indicated on the top of each graph; statistical differences between Min_L and the Min_L-derived mutants indicated by brackets (*p≤0.05, **p≤0.01,...