4. 叶酸的主要表现类型如下: 位点 基因 基因型 类型 rs1801133 C677T MTHFR CC 正常 TT 风险 TC 正常 rs1801131 A1298C MTHFR AA 正常 CC 风险 AC 正常 rs1801394 A66G MTRR GG 风险 AA 正常 AG 风险发布于 2024-09-13 16:00・IP 属地上海 ...
亲，您好。Rs1801133：这是MTHFR基因的一个位点，TT表示该位点上的两个等位基因都是T，即TT基因型。这种基因型与叶酸代谢能力降低有关，可能会影响人体对叶酸的吸收和利用，增加患上某些疾病的风险。亲，基因位点相同，是没有问题的哦，不过亲您平时也要注意身体健康，定期健康检查哦😊 亲，恭喜您哈...
亲亲很高兴为您解答：rs1801133rs1801131检测MTHFR基因rs1801131和rs1801133位点的遗传多态性与NSCL/P的相关性。"rs1801133"和"rs1801131"是两个常见的基因位点，与人类基因组中的多态性相关。这两个位点分别是ACE（血管紧张素转换酶）基因的多态性位点。对于这两个位点的检查，常见的方法是进行基因分型或...
acgttggatggatgaggaggtttctgttac30 210>7 211>16 212>DNA 213>人工序列 400>7 gagctgaccagtgaag16 210>8 211>21 212>DNA 213>人工序列 400>8 agcggcgtgatgatgaaatcg21 210>9 211>16 212>DNA 213>人工序列 400>9 ccacagcttgctcaca16 210>10 211>30 212>DNA 213>人工序列 400>10 acgttggatgaggag...
结果:共纳入18个研究,1216例患者.Meta分析结果显示:显性遗传模式下,(1)rs1801133基因多态性:突变型组(CT+TT基因携带)患者出现骨髓抑制、肝功能损伤、黏膜炎的风险显著性高于野生型组(CC基因携带);贫血、血小板减少、消化道不良反应的发生率在上述两组患者中无显著性差异;24h、48h的MTX血药浓度中,野生型(CC)患者...
Watanabe T, Wu TT, Catalano PJ, Ueki T, Satriano R, Haller DG et al. Molecular predictors of survival after adjuvant chemotherapy for colon cancer. N Engl J Med 2001; 344: 1196–1206. Article CAS PubMed PubMed Central Google Scholar Ge H, Zheng X, Zhao E, Sheng X, Lu S, Cheng...
In the NAFLD CAD group, fasting plasma glucose (FPG) levels of different genotypes of carriers were statistically different (TT vs CT CC: P = 0.047, TT CC vs CT: P = 0.002). Conclusions: The C allele of MTHFR rs1801133 was a risk factor for NAFLD CAD. The CT genoty...
约28%的中国孕妇由于基因为突变纯合型(TT)时,酶活性仅剩30%,叶酸代谢能力差。 约50%的中国孕妇基因为突变杂合型(CT)时,酶活性仅为65%,叶酸代谢能力较差。 仅有约22%的中国孕妇基因正常(CC)时,酶活性100%,叶酸代谢能力正常。 研究发现男性血清叶酸浓度与精子参数呈正相关,MTHFR基因是亚洲男性不育的易感基因。
TT 0(0.0%) 16(100.0%) 0.130 TG 4(10.0%) 36(90.0%) GG 7(17.9%) 32(82.1%) Haplotyping analysis AG haplotype for rs1801133 rs1801131 polymorphism is associated with reduced risk of overall adverse drug reactions, meanwhile GT haplotype for rs1801133 rs1801131 polymorphism was marginally as...
Logistic regression was used to assess the adjusted odds ratios (OR) and 95% confidence intervals (95% CI).Results: The TT genotype of rs1801133 was significantly associated with an increased risk of lung cancer (OR = 2.27, 95% CI = 1.42 - 3.62) while rs1801131 was notassociated with ...