rs1801131是一种基因多态性，也称为MTHFR C677T。AA表示该基因的两个等位基因都是A，即该个体在该位点上的基因型为AA。这意味着该个体在MTHFR基因的C677T位点上没有突变，其编码的酶的活性与正常相同。MTHFR基因编码的酶参与体内同型半胱氨酸代谢，影响体内甲基化反应和DNA合成等生物过程。MTHFR C677...
Association of polymorphisms MTHFR C677T and A1298C with risk of colorectal cancer, genetic and epigenetic characteristic of tumors, and response to chemotherapy. Int J Colorectal Dis 2010; 25: 141–151. Article PubMed Google Scholar Negandhi AA, Hyde A, Dicks E, Pollett W, Younghusband BH...
Association of the MTHFR 1298A>C (rs1801131) polymorphism with speed and strength sports in Russian and Polish athletes 来自 Taylor & Francis 喜欢 0 阅读量: 224 作者: Aleksandra Zarebska,Ildus I. Ahmetov,Stanislaw Sawczyn,Alexandra S. Weiner,Mariusz Kaczmarczyk,Krzysztof Ficek,Agnieszka ...
The single-nucleotide polymorphism (SNP) known as MTHFR 1298A>C (rs1801131) is associated with the combined adverse drug effects (ADEs) on the gastrointestinal, hematologic, and mucosal systems that are linked to the use of methotrexate (MTX) (Haagsma et al. 1999; van Ede et al. 2001; ...