摘要目的探讨TNF -α基因rs1800629位点多态性与汉族人群子宫颈人乳头瘤病毒（HPV ）16型感染风险或HPV16型感染 后子宫颈癌发生风险的相关性。方法研究入选汉族女性679名，共分为3组，分别为HPV16型阳性子宫颈癌患者204例，HPV16型阳性正常人群157例和HPV 阴性正常对照人群318例。通过限制性片段多态法（PCR -RLFP ）...
摘要目的探讨TNF -α基因rs1800629位点多态性与汉族人群子宫颈人乳头瘤病毒（HPV ）16型感染风险或HPV16型感染 后子宫颈癌发生风险的相关性。方法研究入选汉族女性679名，共分为3组，分别为HPV16型阳性子宫颈癌患者204例，HPV16型阳性正常人群157例和HPV 阴性正常对照人群318例。通过限制性片段多态法（PCR -RLFP ）...
目的 探讨TNF-α基因rs1800629位点多态性与汉族人群子宫颈人乳头瘤病-(HPV)16型感染风险或HPV16型感染后子宫颈癌发生风险的相关性.方法 研究入选汉族女性679名,共分为3组,分别为HPV16型阳性子宫颈癌患者204例,HPV16型阳性正常人群157例和HPV阴性正常对照人群318例.通过限制性片段多态法(PCR-RLFP)对rs18006... ...
Ding-Wei Hu1 & Xian-Tao Zeng2,3 Association between tumor necrosis factor-α (TNF-α) G-308A (rs1800629) polymorphism and susceptibility to aggressive periodontitis (AgP) were inconsistent, hence we performed this meta- analysis to clarify the association between them using Comprehensive Met...
Objective To investigate the relationship between TNF-α rs1800629 polymorphism and the risk of HPV16 infection, cervical cancer or cervical cancer after HPV16 infection. Methods Totally 679 Chinese women were involved in this study and divided into three groups , including 204 HPV16 positive cervical...
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通过限制性片段多态法(PCR-RLFP)对rs1800629位点进行基因分型.结果 每2组间TNF-α基因rs1800629位点的等位基因和基因型分布均无明显差异(P>0.05).rs1800629位点多态性与HPV16型感染风险(OR =0.581,95% CI:0.211～1.598,P=0.293),与子宫颈癌发生风险(OR =1.063,95% CI:0.371～3.041,P=0.910),及与HPV16型...
There are reports that the TNFα gene (rs1800629) can be involved in the pathogenesis of metabolic syndrome through an increased production of pro-inflammatory cytokines. Therefore, we have decided to search for the relationship between the TNFα gene polymorphisms and serum levels of proinflammatory...