Prostate stem cell antigen, a presumable organ-dependent tumor suppressor gene, is down-regulated in gallbladder carcinogenesis. Genes Chromosomes Cancer. 2012; 51: 30–41. doi: 10.1002/gcc.20928 PMID: 21936014 8. Sakamoto H, Yoshimura K, Saeki N, Katai H, Shimoda T, Mats...
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cellular architecture and processes of the target organ [110]. Significant progress has been made in the creation of iPSC-induced muscle organoids [111,112,113,114,115,116]. For example, Mavrommatis et al. reported a gradual transition...
found that the polymorphism T-2242C in toll like receptor 4 gene might be related to higher sepsis morbidity rate and organ dysfunction43. Besides, Mansur et al. put forward in their study that the polymorphism rs11536889 in this gene was associated with renal, coagulation and hepatic organ ...
Causes of death Among the 362 subjects who had died during the study period, the organ system most frequently implicated in death was the genitourinary (GU) system. Eighty-eight individuals-24.3% of all who died-died of GU related causes (71 cases of renal failure, 622 Whiteneck et al 80...
Organ bath pharmacology: Mice (C57/BL6; wild type, WT) or soluble guanylyl cyclase knockout (sGC KO; kind gift of Michael Tones, Pfizer; male & female; 20–30 g) were euthanized by cervical dislocation. The thoracic aorta was carefully removed, cleaned of connective tissue and cut into th...
Autoimmune disorders are characterized by the destruction of self-tissues by the immune system. Multiple checkpoints are in place to prevent autoreactivity under normal circumstances. Coexpression of activating and inhibitory Fc receptors (FcR) represents such a checkpoint by establishing a threshold for...
Ein Operationsorgan mit nur wenigen Mitgliedern wäre nützlich, um den Schiffen der Benutzer-länder bei der Durchfahrt durch den Kanal behilflich zu sein. Dadurch würde die Möglichkeit nicht verbaut, zu einer vorläufigen und praktikablen de facto Operationsgrundlage zu kommen. Das ...
but the majority of the studies have shown elevated44,48,49 or similar50,51 levels of sEPCR in sepsis patients as compared to healthy individuals, with one study showing significantly lower sEPCR levels in patients with severe sepsis at the onset of organ failure than in healthy controls52. Th...
To assess the effect of FER rs4957796 on disease severity and organ dysfunction over the first 28 days in the ICU, organ-specific SOFA score analysis was conducted; no differences were found in the organ-specific SOFA scores between the genotypes of FER rs4957796 (Table4). Similarly, the ...