Glioblastoma (GBM) ranks among the most lethal of human cancers, containing glioma stem cells (GSCs) that display therapeutic resistance. Here, we report that the lncRNA INHEG is highly expressed in GSCs compared to differentiated glioma cells (DGCs) and promotes GSC self-renewal and tumorigenici...
FL: 23S rRNA full-length transcript; CL: cleavage product of 23S rRNA. We find that VapC20 recognizes the nucleotides that flank the cleavage site but not other residues in the SRL loop region (Fig. 4c). Moreover, an intact secondary structure of the SRL stem is required for cleavage, ...
immunity, and risk of diseases. Preterm infants, especially in neonatal intensive care units (NICUs), have different gut flora from full-term infants, suggesting in utero microbial colonization. This study examined gut microbiota changes in 92 NICU...
The intensities of the full-size protein bands were plotted in the graph shown below the gel (mutant—blue curve, wt—black curve). b Time course of in vitro expression of sfGFP protein by wt or mutant ribosomes as evaluated by fluorescence (mutant—blue curve, wt—black curve). Graphs ...
Full size image To determine if the sympathoadrenal cells undergo a p53-dependent nucleolar stress response (NSR)41,42,43in thedef+/−;TgMYCN_TT line, we analyzed the p53 protein levels of these cells by immunofluorescence staining. We found that p53 protein was markedly increased at 5 wpf...
Full size image Figure 5 Similarity between LH profiles over time in one patient. Panels a and b are MDS figures which represent the profiles generated from patient UML over a period of time using the V1_V2 and V1 regions, respectively. Panel c is the MDS figure representing the combined...
Full size table The phylogenetic tree estimated for the concatenated SSU rDNA, HSP90 and α-tubulin data is shown in Figure 3. As in the SSU rDNA trees, Spironucleus vortens and Spironucleus salmonicida branch paraphyletically at the base of the Hexamitinae-enteromonad clade with high statisti...
Full size image These results underline that rDNA unit types are not randomly distributed along NOR2 and that they form clusters. To illustrate this, we plotted the frequency of co-occurring pairs identified at 10 kb distance against the frequency of corresponding pairs counted at 20 kb, 30...
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publications on the study of the oral microbiota using sequencing were considered for full-text reading; these were previously reviewed for other reasons (n = 15) or were found during the search for the oral-archaea species (n= 12) taken from bacterial and archaeal species found in the human...