Drug administration route is often classified by the location at which the drug is administered, such as oral or intravenous. The choice of routes in which the medication is given depends not only on convenience and compliance but also on the drug's phar
Lacy, Clifton R.Rodby, Roger A.Insel, JeraldGumprecht, Ernest C.Kostis, John B.Critical Care MedicineLacy CR et al. (1987) Comparison of central and per-ipheral venous routes of medication administration during closed-chest cardiopulmonary resuscitation in humans. Crit Care Med 15: 369 (...
New modes of administration of salmon calcitonin in Paget's disease. Clin Orthop 1987; 217:56–71. Google Scholar Reginster JY. Effect of calcitonin on bone mass and fracture rates. Am J Med 1991;S1:19–22. Google Scholar Overgaard K, Riis BJ, Christiansen C, Hansen MA. Effect of ...
SteadyMed awarded new US patent and patent term extension for PatchPump platform technology Various routes of administration exist, but intravenous is recommended when readily available. Is there a need for further trials on treatment of acute seizures? Under the intentional category, there are two ...
Phase 1; Cell mediated proliferative and IFN-γ responses in cattle following BCG vaccination via different administration routes. Oral vaccination of animals with lyophilized BCG (green circles) did not result in any increases in the frequency of CD4 (A), CD8 (B) or γδ (C) T cell prolife...
Stahl G, Spear ML, Hamosh M. Intravenous administration of lipid emulsions to premature infants. Clin Perinatol 1986;13:133–162. PubMedCASGoogle Scholar Pildes P. Neonatal hyperglycemia. J Pediatr 1986; 109: 905–907. PubMedCASGoogle Scholar ...
Tocilizumab is increasingly used in the treatment of large vessel vasculitis with recent approval for giant cell arteritis. Objective To determine the efficacy and safety of tocilizumab in large vessel vasculitis in a real-life setting using different routes of administration. Methods Retrospective analysi...
For FLU plasma samples, a difference in terminal half-life was observed among routes of administration. Harmonic mean terminal half-lives for FLU were 3.42, 4.48, and 5.39 h for intravenous, intramuscular, and subcutaneous injection, respectively. The mean bioavailability following intramuscular and ...
To address this issue, we aimed to evaluate the toxicological effects of SARS-CoV-2 mRNA vaccine candidates formulated with four different types of lipid nanoparticles in ICR mice, focusing on repeated doses and administration routes. We conducted an extensive analysis in which mice received the ...
Often, another part of the research or testing use of animals is the effective administration of compounds to mice and rats. Although there are a large number of possible administration routes (limited only by the size and organs of the animal), most are not used regularly in research. This...