To make Rosetta protocols available to a wider audience, we previously created a web server called Rosetta Online Server that Includes Everyone (ROSIE), which provides a common environment for hosting web-acces
前言:Rosetta是进行蛋白和分子结构编辑或模拟的一个软件,完整版的Rosetta只支持在Linux和Mac安装。Rosetta的版本有多种,详情参考官方网站Welcome to RosettaCommons。同时,线上版本The Rosetta Online Server that Includes Everyone有多种功能可以使用,简单输入文件即可在服务器上完成操作。下面是电脑安装版的安装步骤。
Web-accessible molecular modeling with Rosetta: the Rosetta Online Server that Includes Everyone (ROSIE). Protein Sci. 27, 259–268 (2018). CAS PubMed Google Scholar Institute for Protein Design. Audacious Project. https://www.ipd.uw.edu/audacious/ (2019). Mulligan, V.K. et al. ...
然而,实施和维护这些服务器需要大量成本。为了更方便地提供协议网络服务器,ROSIE(Rosetta Online Server that Includes Everyone)186,187 (The Rosetta Online Server that Includes Everyone) 实现了协议 "服务器化 "的简单框架。ROSIE 目前包含 25 个网络服务器,并在不断增加新的协议。 结论 Rosetta 软件由一个庞大...
van Zundert, G. C. P. et al. The HADDOCK2.2 web server: user-friendly integrative modeling of biomolecular complexes.J. Mol. Biol.428, 720–725 (2016). PubMedGoogle Scholar Pierce, B. G. et al. ZDOCK server: interactive docking prediction of protein-protein complexes and symmetric multime...
Noncanonical RNA motifs help define the vast complexity of RNA structure and function, and in many cases, these loops and junctions are on the order of only ten nucleotides in size. Unfortunately, despite their small size, there is no reliable method to
Serverification of molecular modeling applications: the Rosetta online server that includes everyone (ROSIE). PLoS One. 2013;8(5):e63906.Lyskov, S. et al. Serverification of Molecular Modeling Applications: The Rosetta Online Server That Includes Everyone (ROSIE). PLoS One 8, e63906, doi:...