定点转基因小鼠是将pCAG-LoxP-STOP-LoxP-DTR-2A-EGFP序列以同源重组的方式嵌入到位于小鼠6号染色体上ROSA26位点,该模式小鼠与组织特异性Cre小鼠交配后得到DTR和EGFP同时组织特异性表达的小鼠。 相关技术资料 运费说明 一、 一次运输: 1. 正常情况下,我司安排运输不少于2只(包括2只)活体模式动物,若客户要求增加运...
To evaluate the contribution of Mist1-positive isthmus stem cells, Lgr5-positive chief cells (hence, largely Mist1-positive chief cells) were ablated by treating Mist1-CreERT2;Lgr5-DTR-GFP;R26-tdTomato mice with diphtheria toxin [11]. Lineage tracing showed an increase in the number of ...