mice.The expression of YFP was induced by different concentrations of 4-hydroxytamoxifen (OHT) with different periods,and the expressing efficiency of YFP in c-kit+ cells was detected by flow cytometry.Results Five out of nine Rosa26R-YFP and ERT2-Cre mice crossbred progenies w...
Using Troy-BAC-CreERT2 mice, Hayakawa et al. also detected a rare population of Troy-positive cells in the isthmus, which could lineage trace and give rise to cancer [11]. They asserted that the Troy-positive chief cells in their mouse model do not lineage trace, which conflicted with ...
流式细胞术检测c-kit+造血干祖细胞中YFP的表达量.结果 Rosa26R-YFP小鼠与ERT2-Cre小鼠的杂交后代共9只,采用基因型分型方法筛选出双阳性转基因小鼠5只;体外培养的c-kit+细胞部分形态发生变化,提示存在细胞分化;流式细胞术检测到c-kit+细胞中YFP表达量可达13.7%.结论 YFP报告基因系统在OHT诱导的ERT2-Cre作用下...
In the background of the Cre reporter mouse strain Rosa26lacZ , we show that the fusion CreERT2 recombinase is normally silent but can be activated ... C Jian,CH Kwon,L Lu,... - 《Genesis》 被引量: 195发表: 2010年 Characterization of mice expressing Ins1 gene promoter driven CreERT...
Testicular degeneration and impaired fertility in conditional Rosa26-CreERT2: Ssb1−/− male mice.Wei, ShiAmanda, L. BainBjoern, SchwerFares, AlEjehCorey, SmithLee, WongHua, ChaiMariska, S. MirandaUda, HoMakoto, Kawaguchi
Reduced retinal astrocyte development in Hif-2αf/f/Rosa26CreERT2 mice.LiJuan, Duan
Nestin-CreERT2/Rosa26YFP miceNeural stem and progenitor cellsSubventricular zoneThe use of inducible transgenic Nestin-CreERT2mice has proved to be an essential research tool for gene targeting and studying the molecular pathways implicated in adult neurogenesis, namely, inside......
The present study examines differences in metabolic and pancreatic islet adaptative responses following streptozotocin (STZ) and hydrocortisone (HC) administration in male and female transgenic GluCreERT2/Rosa26-eYFP mice. Mice received five daily doses of STZ (50 mg/kg, i.p.) or 10 daily dos...
Tamoxifen-inducible and tissue-specific recombinase activity of Cre-ERT2 in SPC-Cre-ERT2/ROSA26R transgenic mice.YaoSong, GuiLianmei, WangXinlun, TianRuie, FengAiping, MaBaiqiang, CaiHongbing, ZhangKaiFeng, Xu