小鼠表皮发绿,自然光下也可看到。 Rosa26-LsL-cas9-tdTomato红色荧光小鼠 Rosa26-LsL-cas9-tdTomato是红色荧光基因编辑工具小鼠。该小鼠与全身表达或组织特异表达Cre重组酶的品系交配后,将会在表达Cre的细胞中删除STOP元件,开启Cas9和tdTomao的表达。可用于活体动物基因编辑的研究,也可当做cre工具鼠的报告小鼠。
Rosa26-LsL-cas9-tdTomato红色荧光小鼠 Rosa26-LsL-cas9-tdTomato是红色荧光基因编辑工具小鼠。该小鼠与全身表达或组织特异表达Cre重组酶的品系交配后,将会在表达Cre的细胞中删除STOP元件,开启Cas9和tdTomao的表达。可用于活体动物基因编辑的研究,也可当做cre工具鼠的报告小鼠。
Rosa26-CAG-LSL-tdTomato | Strain NO. T002249 Knockin (KI) 产品类型: 周龄: 性别: 基因型: 数量: 登录并认证后查看价格 去登录 基本信息 品系详情 品系说明: 应用领域:当存在 Cre 重组酶时,重组后结合转基因或病毒载体递送的sgRNA 实现特定组织器官的基因敲除。 风险提示:该模型根据内部测试结果及技术支...
LSL-Cas9-Rosa26TV 货号:61408-20ul 货号产品名称规格库存价格数量购买 61408-20ulLSL-Cas9-Rosa26TV20ul 立即咨询 +- 产品介绍 相关产品 》产品信息 货号名称规格 61408LSL-Cas9-Rosa26TV 20ul 》产品描述 哺乳细胞基因编辑 》产品简介 Plasmid#61408 ...
LSL-Cas9-Rosa26TV catalog : 61408 more info or order: Addgene product webpage citations: 7 Reference Gierus L, Birand A, Bunting M, Godahewa G, Piltz S, Oh K,et al. Leveraging a natural murine meiotic drive to suppress invasive populations. Proc Natl Acad Sci U S A. 2022;119:e...
ROSA26-specific TALENs or CRISPR-Cas9 system can generate a DNA DSB in ROSA26 in mouse genome, stimulating natural DNA repair mechanism. In the presence of ROSA26 ORF knockin clones, homologous recombination HR happens and integrantes DNA fragment from ORF knockin clone into the safe harbor locus...
Here, we developed a CRISPR-based Rosa26-LSL-dCas9-VPR mouse model for targeted induction of endogenous gene expression using different Adeno-associated virus (AAV) capsid variants for tissue-specific gRNAs delivery. To show applicability of the model, we targeted low-density lipoprotein receptor (...
Product Name:LSL-Cas9-Rosa26TV Synonyms: CAS: MF: MW:0 EINECS: Mol File:Mol File Browse by Nationality Suppliers>Global suppliers Beijing (1)Member(1)All (1) Please select the suppliers Recommend You Select Member Companies Company Name:Beijing Solarbio Science & Tecnology Co., Ltd. ...
The cloned targeting vector contained a NeoR cassette, the human CAG promoter, and a translation interrupting LSL cassette linked with the dCas9-VPR gene fused to a self-cleaving P2A sequence and Egfp gene (Fig. 1A). Characterization of Cre‑dependent and tissue‑specific dCas9‑VPR ...
using the recombinase mediated cassette exchange technology to integrate the dCas9-VPR gene containing cassette into theROSA26locus (Fig.1A). The cloned targeting vector contained a NeoR cassette, the human CAG promoter, and a translation interrupting LSL cassette linked with thedCas9-VPRgene fused...