The roles of ethics in gene drive research and governanceRisk assessmentresponsible innovationphilosophy of scienceresearch ethicssocial acceptanceAnimal biotechnology can be broadly categorized as encompassing the asexual reproduction of animals through cloning, and genetic transformation of animals through the ...
The aim of clinical research is to obtain and to generalize knowledge that elucidates mechanisms, causes and/or pathology of a disease or improves treatments and/or prophylaxis of a disease, in order to develop medical science. Researchers should conduct valuable and ethical study along with to pr...
ethicsFor novice action researchers, issues of roles, politics and ethics are critical, particularly in design. The field of organization development (OD) provides many useful considerations of roles, politics and ethics. This article proposes a systemic design-based framework of ...
The workshop will discuss the challenges of conducting this type of work in a way that can bring sustainable benefits to people living in developing regions.关键词: International development capacity-building cross-cultural design ethics 会议时间: 2009 ...
Members of each DSMB include experts in the disease area, treatment, clinical trial design, biostatistics, and research ethics. The DSMBs are appointed by and report to the sponsor. Their role is to: 每个DSMB的成员包括 疾病领域、治疗、临床试验设计、生物统计学和研究伦理方面的专家 。DSMB由发起人...
Integrated Medical Scientist Program, College of Medicine and Public Health, Comprehensive Cancer Center, The Ohio State University, Columbus, 43210, Ohio, USA Hui-Zi Chen & Gustavo Leone Corresponding author Correspondence to Gustavo Leone. Ethics declarations Competing interests The authors declare no ...
O-linked-N-acetylglucosaminylation (O-GlcNAcylation) is a common and important post-translational modification (PTM) linking O-linked β-N-acetylglucosamine (O-GlcNAc) to serine and threonine residues in proteins. Extensive research indicates its impact
Baranello, L. et al. RNA polymerase II regulates topoisomerase 1 activity to favor efficient transcription.Cell165, 357–371 (2016).Demonstrates the importance of DNA supercoiling and TOP1 in transcription pause–release, and novel TOP1 and Pol II interactions. ...
Members of each DSMB include experts in the disease area, treatment, clinical trial design, biostatistics, and research ethics. The DSMBs are appointed by and report to the sponsor. Their role is to: 每个DSMB的成员包括疾病领域、治疗、临床试验设计、生物统计学和研究伦理方面的专家。DSMB由发起人任...
Copper transporting P-type (P1B-1-) ATPases are essential for cellular homeostasis. Nonetheless, the E1-E1P-E2P-E2 states mechanism of P1B-1-ATPases remains poorly understood. In particular, the role of the intrinsic metal binding domains (MBDs) is enigmatic. Here, four cryo-EM structures...