Examples of crystal-like cluster and distorted icosahedron at the respective threshold values are shown in d and e, respectively. the (extrapolated) perfect structure. In our most deeply supercooled ts(hFamrige.psh3leod,l)dtahsniasdrewcr6a*itr=ebri−itor0an.0ry2y3ibefulodtrscicoQoh6*sea...
The roles discussed in this section refer to HMC users; operating systems running on logical partitions has its own set of users and roles. Each HMC user has an associated task role and a resource role. The task role defines the operations the user can perform. The resource role defines ...
Fig. 1. Overview of GPCR signaling pathways. Canonical GPCR signaling occurs by dissociating heterotrimeric G proteins into Gα and Gβγ subunits. Gα proteins are subdivided into four major subtypes interacting with different downstream effectors. Gs proteins activate AC, resulting in an accumulation...
Anthocyanin is an important class of water-soluble pigments that are widely distributed in various tissues of plants, and it not only facilitates diverse color changes but also plays important roles in various biological processes. Maize silk, serving as an important reproductive organ and displaying ...
2. Structure of ALG-2 Human ALG-2 (22 kDa, 191 amino acids) has an Ala/Gly/Pro/-rich N-terminal tail followed by a penta-EF-hand (PEF) domain (Figure 1), which is a region comprised of approximately 170 amino acid residues containing five repeated helix-loop-heli...
Traditionally, lactate has been considered a ‘waste product’ of cellular metabolism. Recent findings have shown that lactate is a substance that plays an indispensable role in various physiological cellular functions and contributes to energy metabolis
The mechanism of cardiovascular diseases (CVDs) is complex and threatens human health. Cardiomyocyte death is an important participant in the pathophysiological basis of CVDs. Ferroptosis is a new type of iron-dependent programmed cell death caused by ex
The mechanism of cardiovascular diseases (CVDs) is complex and threatens human health. Cardiomyocyte death is an important participant in the pathophysiological basis of CVDs. Ferroptosis is a new type of iron-dependent programmed cell death caused by ex
β2-integrins are adhesion- and mechanoreceptors expressed exclusively on leukocytes. They mediate diverse functions in immunity and are of fundamental importance in processes such as leukocyte trafficking, phagocytosis, T cell and B cell activation and.
In either case, these findings were indicative of an interaction between Cyps and non- structural proteins NS5A and NS5B. Indeed, the viral RNA polymerase NS5B was shown to interact with both CypA and CypB [64,66], and binding of CypB to NS5B was found to stimulate...