Interferon-γ (IFN-γ) plays a key role in activation of cellular immunity and subsequently, stimulation of antitumor immune-response. Based on its cytostatic, pro-apoptotic and antiproliferative functions, IFN-γ is considered potentially useful for adj
and cows under prolonged anestrus or seasonal heat stress [ 9 ]. the combination of ecg and human cg (hcg) is used to induce ovulation in experimental animals [ 12 , 13 ]. in sheep, the oocytes matured in the presence of ecg (20µg/ml) exhibited significantly higher fsh receptor (...
With the development of biomedicine and nanobiotechnology, diverse novel inorganic nanosystems have been generated, which enable multiple theranostic modalities, such as synergistic therapy and multimodal imaging, to be offered as potential alternatives in combating various diseases, especially cancer. Recently...
The MiT/TFE transcription factors play a pivotal role in the regulation of autophagy and lysosomal biogenesis. The subcellular localization and activity of MiT/TFE proteins are primarily regulated through phosphorylation. And the phosphorylated protein i
The regulation of specific target genes by transcription factors is central to our understanding of gene network control in developmental and physiological processes yet how target specificity is achieved is still poorly understood. This is well illustra
Apoptosis, the cell-suicide programme executed by caspases, is critical for maintaining tissue homeostasis, and impaired apoptosis is now recognized to be a key step in tumorigenesis. Whether a cell should live or die is largely determined by the Bcl-2 family of anti- and proapoptotic regulators...
Emerging evidence suggests important roles for lipids and lipid metabolism in several non-apoptotic cell death pathways. Non-apoptotic cell death can be triggered by specific fatty acids. Specific lipids in the plasma membrane are essential for the execution of non-apoptotic cell death. Depletion of...
Host and habitat determine microbial communities of plant-feeding true bugs in different roles. The symbiotic bacterial communities are both shaped by host and habitat but in different ways. Nevertheless, the symbiotic fungal communities are mainly influenced by habitat but not host. These findings she...
Wnts-related signaling pathways have been reported to play roles in the pathogenesis of stress-induced depression-like behaviors. However, there is relatively few direct evidence to indicate the effect of Wnt ligands on this process. Here, we investigate
Koay KL, Syrdal DS, Ashgari-Oskoei M, Walters ML, Dauten- hahn K (2014) Social roles and baseline proxemic preferences for a domestic service robot. Int J Soc Robot 6(4):469-488Koay, K. L., Syrdal, D. S., Ashgari-Oskoei, M., Walters, M. L. & Dautenhahn, K. (2014), ...