important animal model of schizophrenia, more work is needed to understand the role of estrogen in sex and menstrual cycle-related variations in PPI. There may also be a role for progesterone, another ovarian hormone, which shows marked fluctuations over the menstrual cycle (Marshall, 2001) and ...
However, it is not well absorbed unless administered in a micronized form, which has been unavailable until recent years. Addition of a hydroxyl group at C 17 of progesterone results in a loss of progestational activity. Acetylation of the 17-hydroxyl group gives rise to 17-hydroxy-progesterone...
The putative beneficial effects of estrogens on COVID-19 are also disproven by the observation that, in postmenopausal women, the lower risk of worse COVID-19 outcomes is still maintained on age-matched men (https://globalhealth5050.org/the-sex-gender-and-covid-19-project/). In addition, ...
Serum levels of estradiol and progesterone have been directly correlated with the clinical and functional features of asthma. Around 30–40% of women who have asthma experienced worsening of their symptoms during the perimenstrual phase, the so-called perimenstrual asthma. Pos...
In addition to the well-known role of progesterone in reproduction, this steroid regulates important immunomodulatory functions, including reshaping the competence of immune cells and inducing potent anti-inflammatory actions. Progesterone plays a significant role in the maternal reproductive apparatus, for ...
Age oestrogen (ER) and progesterone (P... Soubeyran,Quénel,J M,... - 《British Journal of Cancer》 被引量: 132发表: 1996年 Effects of Hormone Therapy on Cognition and Mood in Recently Postmenopausal Women: Findings from the Randomized, Controlled KEEPS–Cognitive and Affective ... BACK...
Plasma leptin concentrations in postmenopausal women with osteoporosis. Eur J Endocrinol. 2000;142:170–3. PubMed Google Scholar Wang B, Chandrasekera PC, Pippin JJ. Leptin-and leptin receptor-deficient rodent models: relevance for human type 2 diabetes. Curr Diabetes Rev. 2014;10:131–45. ...
Preliminary evidence that progesterone can act as a bone-trophic hormone was initially collected in 1990 (Prior 1990). Since then a number of further reports are available which modify and extend the concepts presented in that paper. In particular, more
It has been shown that PRL and estrogen have immunostimulatory effects, while progesterone and testosterone have immunoinhibitory effects during pregnancy [38]. Thus, high PRL serum level during pregnancy and lactation may provoke immunological disorders and development of autoimmune diseases, including sys...
CentralThe Role of Thyroid Hormone Signaling in the Prevention of Digestive System Cancers. Brown A,Simmen R,Simmen... Brown,R Adam,Simmen,... 被引量: 17发表: 2013年 Amphiregulin Mediates Estrogen, Progesterone, and EGFR Signaling in the Normal Rat Mammary Gland and in Hormone-Dependent Rat ...