Plasma retention (T1/2) was significantly affected by dose and the degree of cross-Unking. Urine flow rates all increased transiently above normal. In rats treated with any 64 kDa interdimerically cross-linked Hb, mild hemoglobinuria was evident and kidney tissue had the highest label ...
The role of the liver and kidney in the metabolism of intravenous testosterone by human subjects. WEST CD, TYLER FH, BROWN H, SAMUELS LT. CD West,H Brown,FH Tyler,... - 《Journal of Clinical Endocrinology & Metabolism》 被引量: 40发表: 1950年 The role of the kidneys in the regulation...
Kidney diseases represent a diverse range of conditions that compromise renal function and structure which characterized by a progressive deterioration of kidney function, may ultimately necessitate dialysis or kidney transplantation as end-stage treatme
Ferrè S,Li XL,Adams-Huet B,et al.Low serum magnesium is associated with faster decline in kidney function:the Dallas Heart Study experience[J].J Investig Med,2019,67(6):987-994.DOI: 10.1136/jim-2018-000966. [14] Hsiao PJ,Liao CY,Kao YH,et al.Comparison of fractional excretion of ...
In diseases of the kidney characterized by irreversible injury, it appears that once a critical level of renal functional deterioration is reached, progression to endstage disease invariably occurs even if the initiating event or condition is resolved or eradicated. Immunopathogenetic mechanisms probably ...
aClears the body of "rubbish" is the main function of kidney. So people often call kidney "scavenger", and "sewer". Kidneys still had several very important functions, such as promoting the formation of red blood cells, bone growth, and so on. Following each described one by one.[transla...
of proteins that occur in these diseases may be aggravated by oxidative damage, and may in turn cause more oxidative damage by interfering with the function of the proteasome. Indeed, it has been shown that proteasomal inhibition increases levels of oxidative damage not only to proteins but also...
8. Thus endothelin infusion caused progressive renal vasoconstriction with similar magnitude increases in both pre- and postglomerular vessels. The vasoconstriction of the kidney caused by endothelin occurred at a dose which did not effect systemic blood pressure. 展开 ...
In Madine-Darby canine kidney cells stably transfected with P-glycoprotein (P-gp) and DPC 333, the transport from B-->A reservoirs exceeded the transport from A-->B by approximately 7-fold. In Caco-2 monolayers and isolated rat ileal mucosa, DPC 333 was transported from basolateral to ...
Different nephrological derangements are observed in severe alcoholics. Until now the direct toxicity of ethanol is only shown in the fetal alcohol syndrome with various malformations of the genitourinary tract. In the adult the kidney is often involved in the development, maintenance and counterregulat...