Coincident with this development in chemical biology has been increased study and appreciation for the importance of ferrous iron during infection and more generally in host–pathogen interaction. Some of the recent findings are surprising and challenge long-standing assumptions about bacterial iron ...
Inflammatory mediators such as interleukin-6 (IL-6) and bacterial-derived lipopolysaccharides (LPS) can directly trigger hepcidin production, leading to the retention of intracellular iron and decreased levels of iron in the circulation [4], [5]. Given that most extracellular pathogens appropriate ...
Iron supply has been suggested to influence phytoplankton biomass, growth rate and species composition, as well as primary productivity in both high and low NO3−surface waters. Recent investigations in the equatorial Pacific suggest that no single factor regulates primary productivity. Rather, an int...
The dynamics of the regular nutrient-induced growth of bacteria are similar to the dynamics of meal-induced intestinal satiety hormone (for example, PYY) release Bacterial molecules and metabolites, whose production depends on bacterial growth phases, regulate intestinal release of satiety hormones System...
Sustainable provision of safe, clean and adequate water supply is a global challenge. Water treatment and desalination technologies remain chemically and energy intensive, ineffective in removing key trace contaminants, and poorly suited to deployment in decentralized (distributed) water treatment systems gl...
Here we report for the first time that bacterial blight of rice can be alleviated by silicon (Si) added. In both inoculated and uninoculated plants, shoot dry weight was significantly higher in the +Si plants than in the −Si plants. A soil-cultured trial showed that disease severity was...
The development of the “waste disposal hypothesis” of autoimmunity, which is related to complement deficiency, highlights the pivotal role of tingible body macrophages, particularly those present in the spleen. Macrophages play a central role in iron homeostasis, primarily in the spleen (red pulp)...
Balkwill DL, Keift TL, Tsukuda T, Kostandarithes HM, Onstott TC, Macnaughton S, Bownas J, Fredrickson JK: Identification of iron-reducing Thermus strains as Thermus scotoductus. Extremophiles. 2004, 8: 37-44. 10.1007/s00792-003-0357-0. Article CAS PubMed Google Scholar Opperman DJ,...
A form of programmed cell death that is dependent on intracellular iron, characterized by the intracellular accumulation of lipid peroxides. Immune thrombocytopenia (ITP). An autoimmune disorder characterized by severe thrombocytopenia secondary to immune destruction of platelets that is responsible for incre...
bacterial iron transport and metabolism functionality is highly correlated with drought enrichment. Using time-series root RNA-Seq data, we demonstrate that iron homeostasis within the root is impacted by drought stress, and that loss of a plant phytosiderophore iron transporter impacts microbial ...