The findings of this review study indicate the important role of irisin in regulating metabolic pathways in the human body. Irisin could be considered as a new therapeutic target in the treatment of metabolic diseases such as insulin resistance and type 2 diabetes.Yazdanimoghaddam F....
The mechanisms, however, by which metabolic signals in turn regulate olfactory perception remain largely unclear. Given the evidence for direct insulin action on olfactory neurons, we tested olfactory performance (olfactory threshold, olfactory discrimination) in 36 subjects of normal- and overweight ...
Insulin-like growth factor-1 (IGF-1) – structure and the role in the human body 来自 Semantic Scholar 喜欢 0 阅读量: 40 作者:A Filus,Z Zdrojewicz 摘要: In the recent years, managed to broadly explore the structure and role of insulin-like growth factors type 1 and 2 (IGF1 I 2)...
39 Similarly, bilirubin levels are inversely correlated with prevalence of type 2 diabetes in humans,40 and mouse models of insulin resistance are protected by haem oxygenase-induced production of bilirubin.41 However, increased haem oxygenase-1 expression is associated with insulin resistance and loss...
Due to insulin-resistance and the increased demand for insulin in the period of pregnancy, some women suffer from debilitated glucose tolerance, which may transform into gestational diabetes mellitus (GDM). Selenium is speculated to be essential for the proper glucose uptake, the regulation of the...
Insulin, a primary metabolic hormone, plays a dominant role in the regulation of food intake. An increase in the level of circulating insulin produced by its prandial release from endogenous stores is associated with the state of satiety. On the other hand, an increase in the insulin level pro...
Since their initial discovery, a growing body of research has implicated that aberrant inflammasome activity contributes to the development of multiple disorders, including metabolic, neurodegenerative, and inflammatory conditions. In recent years, there has been significant progress in identifying the mechani...
aA closer look at the rat brains revealed that those who were not fed DHA supplements had also developed signs of resistance to insulin(胰岛素), a hormone that controls blood sugar and regulates brain function.[translate] a"Insulin is important in the body for controlling blood sugar, but it...
Human MicroRNA targets. PLoS Biol. 2004 Nov;2(11):e363. Epub 2004 Oct 5. B John,AJ Enright,A Aravin,... 被引量: 4334发表: 2004年 MicroRNAs 103 and 107 regulate insulin sensitivity. Defects in insulin signalling are among the most common and earliest defects that predispose an individual...
40 and mouse models of insulin resistance are protected by haem oxygenase-induced production of bilirubin.41 However, increased haem oxygenase-1 expression is associated with insulin resistance and loss of haem oxygenase-1 also appears to be protective against metabolic disorders in mouse.42 In our ...