Bovine eyes were conserved under donor eye conditions in a moist chamber for 48 h. Metabolite levels of glucose, fructose, glucose (glycogen) were determined in corneal epithelium and aqueous humour at certain times by enzymatic optical tests.The role of fructose and glycogen as a nutrient ...
AIMS/HYPOTHESIS: Glycogen accumulation occurs in beta cells of diabetic patients and has been proposed to partly mediate glucotoxicity-induced beta cell dysfunction. However, the role of glycogen metabolism in beta cell function and its contribution to diabetes pathophysiology remain poorly understood. We...
Glycogen synthase kinase-3?? (GSK-3??) is known to affect a diverse range of biological functions controlling gene expression, cellular architecture, and apoptosis. GSK-3?? has recently been identified as one of the important pathogenic mechanisms in motor neuronal death related to amyotrophic lat...
ganglioside glycogene brain function Glycosphingolipids (GSLs) are amphipathic molecules composed of a hydrophilic carbohydrate chain and a hydrophobic ceramide moiety that contains a sphingosine and a FA residue (1). GSLs containing one or more sialic acid residues in the carbohydrate chain are ...
The whole-body computational model developed for this work allows the metabolic control circuitry to be studied under simulated in vivo conditions, providing functional insights that are not evident when individual modules of glycogen regulatory circuitry are examined in isolation. 展开 ...
glycogen. Glycogen is stored in the liver and muscles and in smaller amounts in the other organs and tissues of the body. Energy is derived from glucose by the splitting of the glucose molecules into smaller compounds and oxidizing these to form water, which frees quite a large amount of ...
Conversely, the administration of adrenocorticotrophic hormone or the C-11 oxygenated steroids results in an apparent rapid mobilization of fat 展开 关键词: ADRENAL CORTEX HORMONES GLYCOGEN OBESITY DOI: 10.1210/endo-48-1-56 被引量: 14 年份: 1951 ...
The role of glycogen synthase kinase 3 beta (GSK-3β) in modulating Notch control of vascular smooth muscle cell (vSMC) growth (proliferation and apoptosis) was examined in vitro under varying conditions of cyclic strain and validated in vivo following changes in medial tension and stress. Modul...
Inflammasomes are large protein complexes that play a major role in sensing inflammatory signals and triggering the innate immune response. Each inflammasome complex has three major components: an upstream sensor molecule that is connected to a downstrea
What the papers say: Role of hepatic glycolysis and gluconeogenesis in glycogen synthesis 来自 国家科技图书文献中心 喜欢 0 阅读量: 28 作者:S. J. Pilkis,D. M. Regen,T. H. Claus,A. D. Cherrington 摘要: First page of article DOI: 10.1002/bies.950020609 被引量: 44 ...