Enhanced production of monounsaturated fatty acids (FA) derived from carbohydrate-enriched diets has been implicated in the development of obesity and insulin resistance. The FA elongases Elovl-5 and Elovl-6 are regulated by nutrient and hormone status, and have been shown using intact yeast and ...
(1972) The role of fatty acids in myelin and other important brain structures, in Malnutrition and the Developing Brain Ciba Foundation Symposium , Elsevier, Amsterdam, pp. 31–72.D. Chapman, The role of fatty acids in myelin and other impor- tant brain structures. In: lipids, malnutrition ...
Nature of fatty acids in high fat diets differentially delineates obesity-linked metabolic syndrome components in male and female C57BL/6J mice. Diabetol Metab Syndr 2011; 3: 34. Article CAS Google Scholar Grove KL, Fried SK, Greenberg AS, Xiao XQ, Clegg DJ . A microarray analysis of ...
View Full Article (HTML) Get PDF (172K) Keywords: cardiovascular disease; dietary fat; essential fatty acids; obesity; sustainability Summary Dietary fat should supply at least 15% of food energy including 2.5% energy and 0.5% energy as linoleic acid and alpha-linolenic acid respectively: docosah...
Yiran Li2,4, Fuquan Yang1 & Pingsheng Liu2 Accumulated studies demonstrate that saturated fatty acids (FAs) such as palmitic acid (PA) inhibit insulin signaling in skeletal muscle cells and monounsaturated fatty acids such as oleic acid (OA) reverse the effect of PA on insulin ...
Nature of fatty acids in high fat diets differentially delineates obesity-linked metabolic syndrome components in male and female C57BL/6J mice. Diabetol Metab Syndr 2011; 3: 34. 14 Grove KL, Fried SK, Greenberg AS, Xiao XQ, Clegg DJ. A microarray analysis of sexual dimorphism of adipose ...
Based on these data, several therapeutic approaches to ameliorate obesity and diabetes have been proposed to affect the cellular targets of BA. Abstract Bile acids (BA), long believed to only have lipid-digestive functions, have emerged as novel metabolic modulators. They have important endocrine ...
There exists a conjecture that SGLT2i exhibit the capacity to elevate levels of ketone bodies and free fatty acids, potentially influencing renal and cardiovascular metabolism through the process of ketogenesis [60]. These findings may contribute to a better understanding of the mechanisms underlying ...
Antibiotic resistance has been an ongoing challenge that has emerged almost immediately after the initial discovery of antibiotics and requires the development of innovative new antibiotics and antibiotic combinations that can effectively mitigate the development of resistance. More than 35,000 people die ...
However, the roles of AA and other unsaturated fatty acids in the process of IK(Ca) activation by membrane stretch in gastric myocytes remains unclear. In the present study, we therefore investigated the effects of AA and its metabolites on hyposmotic membrane stretch-induced increases in IK(Ca...