Biological estrogen actions on male reproductive system are summarized with particular regard to the effects of congenital estrogen deprivation in men. The effects of estrogen on spermato gene sis, hormonal secretion and gonadotropin feedback and on sexual behavior are discussed. It is remarked that ...
Estrogen improves bone density and reduces the risk of osteoporosis for both women and men. Estrogen helps prepare a woman’s body for pregnancy and in males, estrogen assists in the growth and maturity of sperm. In addition to reproductive function, estrogen also boosts libido and sexual desire...
Women with colorectal cancer (CRC) have a significant survival advantage over men. Sex influences on the tumour microenvironment (TME) are not well characterised, despite the importance of immune response in CRC. We hypothesised that sex-divergent immune responses could contribute to survival. Methods...
Gonadal Steroids hormones play an important role in the reproductive and non-reproductive system. Estrogen has important rule in cardiovascular system as it has vasodilator effect and reduces or prevents platelet activation. In addition, it improves the profile of circulating lipoproteins. All of which...
RANKL expression in B lymphocytes, but not T lymphocytes, contributes to the loss of trabecular bone caused by estrogen deficiency. In this Review, we summarize this evidence and discuss its implications for understanding the regulation of trabecular and cortical bone mass; the integration of ...
Although the mechanisms underlying gender-related differences in body fat distribution and lipid homeostasis remain to be fully determined, the reported differences appear to principally reflect the actions of the sex steroid hormone estrogen on whole-body lipid metabolism. In the present review, we ...
Moreover, selective estrogen receptor inhibitors (SERMs), such as tamoxifen, have also tissue-specific pro-estrogenic effects and one of the most notorious adverse event with SERMs is venous thromboembolism, a life-threatening event in COVID-19. Hence, the role of sex hormones in COVID-19 ...
Role of emotional processing in depressive responses to sex-hormone manipulation: a pharmacological fMRI study Mood disorders are among the most common causes for disability and constitute a major and severe public health problem.1The prevalence is twice as high in women relative to men.2Postpartum...
Various parameters of sexual functioning were assessed in a prospective, crossover investigation of 53 surgically menopausal women. Patients randomly received either an estrogen-androgen combined preparation, an estrogen-alone drug, an a... BB Sherwin,MM Gelfand,W Brender - 《Psychosomatic Medicine》 ...
Given both the high prevalence of anxiety disorders in women and the fact that little is known about the mechanisms of gender differences in anxiety, our primary aim in this study was to investigate the neurobiological mechanisms underlying sex differenc