Estrogen improves bone density and reduces the risk of osteoporosis for both women and men. Estrogen helps prepare a woman’s body for pregnancy and in males, estrogen assists in the growth and maturity of sperm. In addition to reproductive function, estrogen also boosts libido and sexual desire...
Developments in research regarding the role of estrogen; Effects of estrogen deficiency or resistance in males; Dissociation brought by estrogen deficiency in both sexes.GrumbachDepartmentM.DepartmentM.DepartmentHormone ResearchGrumbach M.Ɇ. The role of estrogen in the male and female. Horm. Res. ...
Experiments using mice with inactivated sex steroid receptors demonstrated that both activation of the estrogen receptor (ER)伪 and activation of the androgen receptor result in a stimulatory effect on both the cortical and trabecular bone mass in males. ER尾 is of no importance for the skeleton ...
RANKL expression in B lymphocytes, but not T lymphocytes, contributes to the loss of trabecular bone caused by estrogen deficiency. In this Review, we summarize this evidence and discuss its implications for understanding the regulation of trabecular and cortical bone mass; the integration of ...
about 15% of the genes in the inactive X chromosome escape the inactivation process [50]. This may create dimorphisms in immune response as the X chromosome has the highest number of immune-related genes [5,102]. Sex hormones such as estrogen, progesterone, and testosterone change the immune...
supposedly because of a neuroprotective role of estrogen in women (Häfner et al, 1998;Kulkarni, 2009). Female schizophrenia patients also show greater symptom severity during the periods of low estrogen (eg, post-partum) and lower symptom severity during the periods of high estrogen (eg, pregn...
estrogen receptor (ER)伪 and activation of the androgen receptor result in a stimulatory effect on both the cortical and trabecular bone mass in males. ... C Ohlsson - 《European Journal of Endocrinology》 被引量: 84发表: 2009年 The Effect of Photoperiod on Sexual Maturation, Appetite and Gr...
These data demonstrate survival-associated differences in the immune response of males and females to metastatic CRC. Females showed changes in cytokine production accompanied by increased immune cell populations, biased toward Th2-axis phenotypes. Key differences in the immune response to CRC correlated...
Natural selection clearly favors the accumulation and storage of lipids in humans, predisposing women to store excess fat in gluteal regions and predisposing males to store excess fat in visceral regions. In addition, gender differences are reported with respect to the concentrations of circulating lipi...
Cardiovascular diseases including heart failure are the major cause of morbidity and mortality in both males and females of all ages and ethnicities. Premenopausal females are relatively protected from cardiovascular diseases compared to age-matched males; however, the risk of these health hazards increas...