Dopamine quinones3,4-DihydroxyphenylacetaldehydeNeurodegenerationPathogenesisParkinson's diseaseReactive oxygen speciesTherapeutic strategiesREDUCED VESICULAR STORAGEMETHYL-PARA-TYROSINEA pathological feature of Parkinson's disease (PD) is the progressive loss of dopaminergic neurons and decreased dopamine (DA) ...
Much recent work has focused on the role of dopamine in information acquisition (learning). Here we investigate the role of dopamine in consolidating information over time (memory). We recently tested patients with Parkinson's ON and OFF medication on a computerised cognitive task of learning, ...
Here we investigate the role of dopamine in consolidating information over time (memory). We recently tested patients with Parkinson's ON and OFF medication on a computerised cognitive task of learning, reasoning and memory. Dopamine therapy did not influence initial learning, but did significantly ...
The article presents information on some recent developments in Parkinson's disease. Some of the developments are: Levodopa and the progression of Parkinson's disease; Levodopa-induced changes in synaptic dopamine levels increase with pr... JP Price - 《Yale Journal of Biology & Medicine》 被引量...
O Alexinschi,EA Sirieanu - 《Bulletin of Integrative Psychiatry》 被引量: 0发表: 2024年 Dopamine D3 Agonists in the Treatment of Parkinson&aposs Disease Parkinson&aposs disease (PD) is t he second most common form of neurodegenerative disorders that results from the progressive loss of dop...
Dopamine (DA) not only functions as a neurotransmitter, a chemical messenger between neurons by which one neuron triggers another, researchers have found. It also appears to coordinate the activity of a particular neural circuitry. In studies with mice,
We investigated the effect of striatal dopamine depletion [in Parkinson's disease (PD)] on the ability to switch between independent action plans. PD ... RC Helmich,E Aarts,FP De Lange,... - 《Journal of Neuroscience》 被引量: 132发表: 2009年 Increased Dependence of Action Selection on ...
Glutamate/dopamine D1/D2 balance in the basal ganglia and its relevance to Parkinson's disease. The recent availability of selective ligands for NMDA and AMPA receptors has enabled neuroscientists to test the hypothesis that Parkinson' disease is a gl... MS Starr - 《Synapse》 被引量: 486发...
Parkinson's disease (PD) patients display motor symptoms, e.g. tremor, rigidity and bradykinesia, largely due to a dramatic loss of dopaminergic neurons in the substantia nigra. Grafts of human embryonic dopamine neurons can survive in the striatum and reduce several of the motor symptoms. Severa...
Role of mitochondria in cell death of dopamine neurons in Parkinson diseaseRole of mitochondria in cell death of dopamine neurons in Parkinson diseasedoi:10.1111/j.1447-0594.2004.00197.xWakakoSectionMaruyamaSectionMasayoSectionNagaiSectionMakotoSection...