Biogenesis of extracellular vesicles in male and female reproductive systems. EVs are composed of functional proteins, mRNA, and microRNA. In particular, the protein content of EVs depends on the cell type from which they are secreted. Biogenesis of extracellular vesicle (EV) subtypes such as exos...
While there are limited clinical data regarding most chemical exposures and human reproduction, studies in laboratory animal models and wildlife underscore the vulnerability of the female reproductive system to many environmental insults during various windows of development and across the life cycle. ...
Biogenesis of extracellular vesicles in male and female reproductive systems. EVs are composed of functional proteins, mRNA, and microRNA. In particular, the protein content of EVs depends on the cell type from which they are secreted. Biogenesis of extracellular vesicle (EV) subtypes such as exos...
Background: Progesterone is a key hormonal regulator of the female reproductive system. It plays a major role to prepare the uterus for implantation and in the establishment and maintenance of pregnancy. Actions of progesterone on the uterine tissues (endometrium, myometrium and cervix) are mediated...
IIIs are especially important for antiviral defense at epithelial barrier surfaces [5], particularly in the lung [6], gut [7], and female reproductive tract [8], as well as in the human liver [9]. IFN-IIIs exert antiviral effects that are very similar to those of IFN-Is. Vertebrate ...
Implantation is the key initial complex stage of pregnancy. Several factors are involved in implantation, but acute and controlled inflammation has been shown to play as a key role. On the other hand, the role of viral infections in directly infecting bl
Disorders of the fallopian tube play a very important role in both infertility and gynaecological oncology. Tubal factor infertility is considered among the leading causes of female factor infertility. Many tubal disorders are related to infertility including congenital anomalies, acute and chronic ...
gonorrhoeae is unable to invade the squamous epithelium of the vagina and ectocer- vix, but rather colonizes and transmigrates across the columnar epithelium of the uterine endocervix.3 In women, infection with gonorrhea usually remains localized to the lower reproductive tract, where it can induce...
Intriguingly, the class of antidepressant drugs, such as selective serotonin reuptake inhibitors (SSRIs), may also contribute to generating resistant microorganisms with a profound disturbing role in local cervix-vagina homeostasis. Therefore, we proposed the possible involvement of SSRIs in the onset ...
“really letting the woman kind of guide that [the physical exam]… and what that looks like and letting them just tell me what’s okay and what’s not okay, versus me saying, I’m going to check your cervix now.” (CNM) “I make sure that every woman knows that you have to giv...