C., Castillo-Armengol, J., Lagarrigue, S., and Fajas, L. (2018). Role of cell cycle regulators in adipose tissue and whole body energy homeostasis. Cell. Mol. Life Sci. 75, 975-987. doi: 10.1007/s00018-017-2668-9Lopez-Mejia I C, Castillo-Armengol J, Lagarrigue S, et al. ...
cell cycle regulatorscell growthendolysosomesmetabolismmitochondriaAdapting to changes in nutrient availability and environmental conditions is a fundamental property of cells. This adaptation requires a multi-directional coordination between metabolism, growth, and the cell cycle regulators (consisting of the ...
Bahnassy AA,Zekri AR,Saleh M,et al.The possible role of cell cycle regulators in multistep process of HPV-associated cervical carcinoma.BMC Clinical Pathology. 2007Bahnassy AA, Zekri AR, Saleh M, et al. The possible role of cell cycle regulators in multistep process of HPV-associated ...
and the abnormal expression of cell cycle-related proteins gives tumor cells their invasive, metastatic, drug-resistance, and anti-apoptotic abilities. Recently, an increasing number of cell cycle-associated proteins have become the candidate biomarkers for early diagnosis...
Among the genes most significantly deregulated upon SMARCA4 knock-down were several of known significance in PCa progression, including: upregulation of cell cycle regulators CDKN1A (p21) and BTG2 (in both LNCaP and 22Rv1 cell lines), downregulation of E2F targets (in both cell lines), ...
Cancer immunotherapy has rapidly transformed cancer treatment, yet resistance remains a significant hurdle, limiting its efficacy in many patients. Circular RNAs (circRNAs), a novel class of non-coding RNAs, have emerged as pivotal regulators of gene exp
Drosophila neuroblast asymmetric divisions: cell cycle regulators, asymmetric protein localization, and tumorigenesis J. Cell. Biol., 180 (2008), pp. 267-272 CrossrefView in ScopusGoogle Scholar Choksi et al., 2006 Choksi S.P., Southall T.D., Bossing T., Edoff K., de Wit E., Fischer ...
However, one clear point is that growth differences alone are not sufficient to induce loser cell elimination by cell competition. This is illustrated by the fact that increasing proliferation in clones of cells in the wing disc by overexpression of the cell-cycle regulators cyclin D and cyclin-...
and the expression of cell-cycle regulators including CCNA2 and CDK2, and thereby modulates adipogenesis52,148. Furthermore, YTHDF1 was recently revealed to specifically recognize m6A-modified transcript of MTCH2 (mitochondrial carrier homology 2) in Jinhua pigs (obese-type breed with higher levels...
Molecular pathology of malignant gliomas. Annu Rev Pathol 2006; 1: 97–117. Article CAS PubMed Google Scholar Kessenbrock K, Plaks V, Werb Z . Matrix metalloproteinases: regulators of the tumor microenvironment. Cell 2010; 141: 52–67. Article CAS PubMed PubMed Central Google Scholar Rao...