The article reports on the role of blood vessels in tendon pain and pathology. The article defines normal tendon function and pathological tendon function, and discusses the ways blood vessels are related to the causation of pain in pathological tendons. The article also discusses a treatment for ...
The total operative time is eliminated and the average blood loss is significantly decreased. It is important to note that this technique should not be applied near the hilum or the vena cava to avoid damage of these structures. 展开
VEGF stimulates the regrowth of blood vessels into the injury site, so that oxygen and nutrient levels can begin to return to normal values. The general pattern of bone cell activity following fracture or osteotomy is broadly consistent with the known responses of osteoblasts and osteoclasts to ...
The blood supply to bone is delivered to the endosteal cavity by nutrient arteries, then flows through marrow sinusoids before exiting via numerous small vessels that ramify through the cortex. The marrow cavity affords a range of vascular niches that are thought to regulate the growth and ...
of the National Academy of Sciencesand funded by Wellcome, shows that blood vessels can increase the number of neural stem cells inside a living organism. This could be important for the design of stem cell-based therapies that aim to regenerate diseased or damaged parts of the nervous system....
The advent of immune checkpoint inhibition (ICI) using antibodies against PD1 and its ligand PDL1 has prompted substantial efforts to develop complementary drugs. Although many of these are antibodies directed against additional checkpoint proteins, ther
Adequate supply of blood and structural and functional integrity of blood vessels are key to normal brain functioning. On the other hand, cerebral blood flow shortfalls and blood–brain barrier dysfunction are early findings in neurodegenerative disorders in humans and animal models. Here we first ex...
The development and remodeling of placental blood vessel determine the function of the placenta, and furthermore intrauterine fetal growth. Placental vascular abnormalities will directly lead to pregnancy complications such as preeclampsia, and ultimately affect pregnancy outcomes. Notch signaling pathway is ...
The de-endothelialization of the vessels increased this effect. In addition, activated leukocytes increased the platelet aggregation. It was concluded, that activation of leukocytes can trigger thrombogenesis, angiospasm, microembolic syndrome and other disturbances of blood circulation....
The cardiovascular system significantly contributes to the functionality of the skeletal system.126As an essential component of blood vessels, ECs are located in the inner layer of blood vessels and often internalize and secrete substances.127Studies have shown that EVs secreted by ECs (EC-EVs) can...