Lipids in Health & DiseaseShao X, Yang W, Shao X, Qiu C, Wang X, Wang Y. The role of active brown adipose tissue (aBAT) in lipid metabolism in healthy Chinese adults. Lipids Health Dis. (2016) 15:138. doi: 10.1186/s12944-016-0310-8...
Lipid metabolismcytokinefatty acidobesityatherosclerosissteatohepatitisAdipose tissue has been considered as a crucial source of certain pro-inflammatory cytokines; conversely, these pro-inflammatory cytokines are involved in regulating the proliferation and apoptosis of adipocytes, promoting lipolysis, inhibiting ...
Methionine–choline-deficient (MCD) diet is a widely used dietary model of non-alcoholic steatohepatitis (NASH) in rodents. However, the contribution of adipose tissue to MCD-induced steatosis, and inflammation as features of NASH are not fully understood. The goal of this study was to elucidate...
Weight loss induces an inflammatory response in adipose tissue. Evidence for the involvement of epigenetic modifications, in particular microRNAs, in weight regain is sparse. Knowledge of weight regain after weight loss is mainly based on associations, and so research into the causality of such associ...
We have studied the effects of somatostatin on lipid metabolism in liver and adipose tissue of fasted mice. The animals were injected subcutaneously with 8 μg somatostatin and killed 5 min after injection. In vivo incorporation of [ 14C]acetate into triglycerides in both tissues and into hepatic...
Role of Adipose Tissue Nutrient/Vitamin Metabolism in Physiological and Altered Metabolic Settings: Glucose-dependent insulinotropic polypeptide promotes lipid ... S Thondam,C Daousi,J Wilding,... - 《American Journal of Physiology》 被引量: 0发表: 2017年 Developing a mouse model to study the me...
Periostin drives extracellular matrix degradation, stemness, and chemoresistance by activating the MAPK/ERK signaling pathway in triple–negative breast cancer cells Adipose tissue, which is mainly composed of adipocytes, is a crucial component of the tumor microenvironment, particularly in breast cancer...
The adipose tissue metabolism: role of testosterone and dehydroepiandrosterone. Int J Obes Relat Metab Disord. 2000; 24(Suppl 2):S59-S63.De Pergola G (2000) The adipose tissue metabolism: role of tes- tosterone and dehydroepiandrosterone. Int J Obes Relat Metab Disord 24, 59- 63.The ...
•Inability to store lipids in adipocytes, whole body energy storage units, is associated with T2D.•Adipocyte LD is uniquely organized to support appropriate in- and outflux of unesterified lipids.•A few known adipose specific LD proteins orchestrate LD growth by limiting lipid lipotoxic effe...
Adipose tissue plays an important role in body homeostasis by producing and secreting several bioactive proteins known as adipokines: adiponectin, leptin, resistin, visfatin, and apelin, which are involved in the regulation of food intake, glucose and lipid metabolism, and insulin action. There can ...