Although a functioning excitatory synapse contains both alpha-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid (AMPA) and N-methyl-D-aspartate (NMDA) receptors in the postsynaptic membrane, recent evidence suggests that dorsal horn neurons contain some "silent" synapses, which exhibit purely ...
GABA depolarization is required for experience-dependent synapse unsilencing in adult-born neurons. J Neurosci. 2013;33:6614–22. CAS PubMed PubMed Central Google Scholar Heigele S, Sultan S, Toni N, Bischofberger J. Bidirectional GABAergic control of action potential firing in newborn ...
The immunocytochemical staining patterns of 37 neuron-specific monoclonal antibodies previously described fell into four groups: (i) anti-synapse-associate... LA Sternberger,NH Sternberger 被引量: 0发表: 2019年 Percutaneous transluminal angioplasty and stenting for pulmonary stenosis due to Takayasu's ...
Cancedda, L., and Poo, M. M. (2009). "Synapse formation and elimination: competition and the role of activity," in Encyclopedia of Neuroscience, ed L. R. Squire (Oxford: Academic Press), 697-703.Cancedda L, Poo MM. Synapse formation and elimination: competition and the role of ...
Cocaine use is associated with breach in the blood brain barrier (BBB) and increased HIV-1 neuro-invasion. We show that the cellular enzyme “Prolidase” plays a key role in cocaine-induced disruption of the BBB. We established a barrier model to mimic t
C Galvin,I Ninan - 《Neuropsychopharmacology Official Publication of the American College of Neuropsychopharmacology》 被引量: 26发表: 2014年 Effects of long-term treatment with estrogen and medroxyprogesterone acetate on synapse number in the medial prefrontal cortex of aged female rats The present st...
AP-1 functions upstream of CREB to control synaptic plasticity in Drosophila Here, using a Drosophila model synapse, we analyse cellular functions and regulation of the best known immediate early transcription factor, AP-1; a ... S Sanyal,DJ Sandstrom,CA Hoeffer,... - 《Nature》 被引量: 35...
Even after successful extinction, conditioned fear can return. Strengthening the consolidation of the fear-inhibitory safety memory formed during extinction is one way to counteract return of fear. In a previous study, we found that post-extinction L-DOP
Obesity is a health condition that has reached pandemic levels and is implicated in the development and progression of type 2 diabetes mellitus, cancer and heart failure. A key characteristic of obesity is the activation of stress-activated protein kinas
BDNF mRNA expression in rat hippocampus and prefrontal cortex: effects of neonatal ventral hippocampal damage and antipsychotic drugs. Brain-derived neurotrophic factor (BDNF) plays an important role in development, synapse remodelling and responses to stress and injury. Its abnormal expre... BK Lipska...