A growing body of evidence shows that Tregs are not only important for maintaining immune balance at the periphery but also contribute to self-tolerance and immune privilege in the central nervous system. In this article, we first review the current status of knowledge concerning the development ...
However, body weight is known to be a powerful co-variable and this correlation can lead to an association that is true but potentially biologically misleading. The importance of considering weight in interpreting phenotypes, and doing so correctly via regression, has been raised previously.15–17 ...
Majka and A. Dembiński - 《Regulatory Peptides》 被引量: 113发表: 1991年 Comparison of the biological efficacy of DL-methionine and hydroxy4-methylthiobutanoic acid (HMB) in pigs and poultry High-tannin hulls of faba beans and isolated tannins were shown to induce a rapid hypertrophy of ...
To navigate the complex MedTech regulatory landscape often comes with challenges. This video helps you navigate the conformity journey to place your product on the market. It also provides an overview of medical devices and IVDs regulatory framework, as well as BSI Regulatory Services offer for ...
A growing body of evidence indicates that reactive astrocytes are not bystanders during disease development [5]. However, their functions and regulatory mechanisms remain elusive. Reactive astrocytes responding to pathological insults are distinct from normal astrocytes in morphology, functions and molecular...
In particular, the protein content of EVs depends on the cell type from which they are secreted. Biogenesis of extracellular vesicle (EV) subtypes such as exosomes, MV, syncytial nuclear aggregates and apoptotic bodies. EVs are intraluminal vesicles which are released when a multivesicular body ...
Extensive genetic and molecular studies have been carried out during the last decade or so, and, as a result, a large body of information is available on the regulatory components of ABA-responsive gene expression under stress conditions. In this article, recent advances in the area are summa ...
Activation involves alterations in cellular protrusions, increases in cell body size and proliferation, and enhanced phagocytosis, collectively referred to as microglial proliferation. This process is mediated through signaling pathways such as nuclear factor-kappa B (NF-κB), interferon regulatory factor ...
Then, through motif enrichment analysis based on differentially expressed gene sets between erection and flaccid conditions in SMCs, we identified the AP1 binding motif as a highly enriched regulatory element (Fig. S1d). It has been previously shown that AP1 and TEAD serve as YAP/TAZ ...
Bone mainly functions as a supportive framework for the whole body and is the major regulator of calcium homeostasis and hematopoietic function. Recently, an increasing number of studies have characterized the significance of bone as an endocrine organ, suggesting that bone-derived factors regulate loca...