female The absence of functional ARs resulted in a partial demasculinization of roosters and a partial defeminization of hens, challenging the concept of a default sex of male and female genomes. Specifically, males without ARs do not develop the overall female phenotype, and females without ARs...
6. Quelques Mots Sur lAcide Lactique et les Lactates Alcalins et Terreux sur leurs Roles dans lEconomie Animale et specialement dans lActe de la Digestion [O] . 1865 机译:乳酸碱和土质乳酸在动物经济学中的作用尤其是在消化过程中的作用 7. La gouvernance de la culture : le rôle des...
Screening for positive regulators of multi-drug resistance DNA manipulation generally followed standard practice.39 A genomic library was developed by partial Sau3AI digestion of the chromosomal DNA as follows. Chromosomal DNA prepared from an overnight culture of the wild-type strain MG165537 was ...
The blasticidin-resistance cassette of pGL842 was then replaced, by SpeI/BamHI digestion, by the hygromycin-resistance cassette of pGL720 or by the bleomycin- resistance cassette of pGL726, yielding pGL849 and pGL1033, respectively. The sequences of the primers used for this study are given ...
After the digestion, the peptides were cleaned on an Oasis HLB 96-well plate (HLB 30 mg, Waters, the USA), and the eluted samples were concentrated with an Eppendorf Concentrator plus system (Eppendorf, Hamburg, Germany). The concentrated peptides were resolved in 100 µL water containing...
[254,280,284]. Besides secreted cathepsins, cathepsins in lysosomes of TAMs could be responsible for the digestion of internalized collagen fragment from tumor microenvironment [285]. Owning, at least in part, to extracellular matrix degradation, cathepsins augment angiogenesis. It has been reported...
The abnormal accumulation of digestion products in the lysosomal lumen will progressively disrupt its basic functions, including trafficking and the ability to fuse with autophagosomes, which in turn lead to neurodegeneration, metabolic imbalance and severe growth retardation [32, 33]. LSDs are usually...
Bhagavan, H.N.; Chopra, R.K.; Craft, N.E.; Chitchumroonchokchai, C.; Failla, M.L. Assessment of coenzyme Q10 absorption using an in vitro digestion-Caco-2 cell model. Int. J. Pharm. 2007, 333, 112–117. [CrossRef] [PubMed] 105. Svensson, M.; Malm,...
et al. Digestion of chromatin in apoptotic cell microparticles prevents autoimmunity. Cell 166, 88–101 (2016). CAS PubMed PubMed Central Google Scholar Sjoberg, A. P., Trouw, L. A. & Blom, A. M. Complement activation and inhibition: a delicate balance. Trends Immunol. 30, 83–90 (...
Protein phosphorylation is recognized as the primary mechanism for the transduction of extracellular stimuli into intracellular events (Cohen, 1982; Nestler et al.,1984). Ineukaryotes, for example, all of the biochemical actions of cAMP have been attribu