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Intestinal secretory cells such as colonic goblet which produce mucin, and small intestinal crypt paneth cells, which produce defensins, lysozyme, antimicrobial lectins and collectins and so are extensively involved in protein manufacture, processing and granular storage of proteins that m...
the rationale and is thought to underlie the remarkable beneficial effects of cell and gene therapeutic approaches for lysosomal storage disorders in mice and humans31,44. However, its direct consequences were not yet corroborated in a physiologicalin vitromodel of myelination. Thus, iSCs might be e...