Associations of homologous RNA-binding motif gene on the X chromosome (RBMX) and its like sequence on chromosome 9 (RBMXL9) with non-obstructive azoospermia 文档格式: .pdf 文档大小: 150.02K 文档页数: 6页 顶/踩数: 0/0 收藏人数: 0
To discover novel RBP regulators of leukemia, we performed an in vivo pooled shRNA screen of 127 MSI2 direct protein interactors and associated genes (Vu et al. Nat Gen. 2017). In this screen, shRNAs specific to the RBP RBMX (RNA binding motif protein, X-linked) were selectively ...
RNA binding motif protein 10 (RBM10) is located on the X chromosome (Xp11.3) and encodes an RNA binding protein. Previous studies revealed that RBM10 functions as an auxiliary splicing factor to promote exon skipping by binding to adjacent intronic regions [20], [21], [22]. RBM10 germline...
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Objective We have used long-read single molecule, real-time (SMRT) sequencing to fully characterize a ~12Mb genomic region on chromosome Xq24-q27, significantly linked to bipolar disorder (BD) in an extended family from a genetic sub-isolate. This family segregates BD in at least four gener...
Diversity of RNA-binding proteins modulating post-transcriptional regulation of protein expression in the maturing mammalian oocyte. Cells 9, 662 (2020). Article CAS PubMed Central Google Scholar Lee, M. H. & Schedl, T. Identification of in vivo mRNA targets of GLD-1, a maxi-KH motif ...
Rbm24 is a member of the RNA binding protein family, based upon the identification of a RNA recognition motif (RRM) in amino acid residues 12-84. RRMs are the most common and best characterized RNA binding modules with many functioning in most post-transcriptional processes [6]. The RRM is...
Next, we created a list of all K-mers appearing in the conserved human and yeast proteins; K-mers containing an ‘X’ or ‘U’ were excluded. A table counting the repeat number of each motif in each protein was computed for each of the five organisms. The tables were combined to a ...
In the case of the RBMY (RNA binding motif gene on chromosome Y) protein, however, it was shown that, in addition to the sequence-specific recognition of the loop by the β-sheet, a loop of the RRM also inserts into the major groove of the stem in a shape-specific manner (Fig. ...
RNA-binding motif protein 38 (RNPC1), also known as RBM38, is located on chromosome 20q13.31. It belongs to the RNA recognition motif (RRM) family of RBPs, all containing a putative RNA recognition motif, which shares sequence similarities with those in Hu antigen R (HuR) and Musashi [...