DNA and RNA are both types of nucleic acids, which are molecules that contain sets of instructions for cells to make genetic information and proteins. However, there are significant differences between the two of them.This guide will compare and contrast DNA and RNA in terms of structure, funct...
While DNA has the instructions on how to make proteins, it is RNA that actually provides these instructions to theribosomes, organelles in the cell that act as “protein factories” You see,DNAnever actually leaves the cell’s nucleus. The nucleus instead builds a single-threaded molecule calle...
1) Compare the differences between DNA and RNA, structurally and functionally. Can you explain why DNA is more favorable as a genetic material? Answer: The differences between DNA and RNA in the structure (1) DNA contains deoxyribose in contrast to the ribose in RNA. (2) DNA has the thymi...
The rarity of RNA editing has been challenged by a recent comparison of human RNA and DNA sequence data from 27 individuals, which revealed that over 10,000 human exonic sites appear to exhibit RNA-DNA differences (RDDs). Many of these differences could not have been caused by either of ...
measurements taken in two samples, by transforming the data onto M (log ratio) and A (mean average) scales, then plotting these values. Though originally applied in the context of two channelDNA microarraygene expression data, MA plots are also used to visualisehigh-throughput sequencinganalysis....
As long-read sequencing technologies continue to advance, the possibility of obtaining maps of DNA and RNA modifications at single-molecule resolution has become a reality. Here we highlight the opportunities and challenges posed by the use of long-read sequencing technologies to study epigenetic and...
(TP) conformation that dominates under hypoxia, where the GAIT element and stem stability sequence are annealed to each other. The differences in the MFE model and the TP conformation described in the literature occur primarily at the hnRNP L binding site. The literature model is based on ...
The improved detection of the 10-fold differences in RNA copy numbers between sample series (resulting in an average slope within 6% of expected value) also indicates that the pre-amplification process does not introduce bias into the detection of transcripts which cover a wide dynamic range. ...
DNA damage response serves as a crucial barrier against the malignant transformation of cells, with the DNA repair system playing a key role in maintaining cellular homeostasis. Interestingly, RNA editing has been observed in transcripts of genes involved in DNA repair systems, suggesting that RNA ...
Correlated DNA/RNA over-expression can then be confirmed with microarray data. The resulting data is further analyzed by a modeling and simulation computational system developed by our team specifically for clinical application including, but not limited to, gene set enrichment analysis and network ...