TYMV RNA as an Amino-acid DonorNo Abstract available for this article.doi:10.1038/241310b0NoneNature Publishing Group UKNature
TYMV RNA as an Amino-acid Donor THE single stranded genomic RNA of turnip yellow mosaic virus (TYMV) has some striking similarities to transfer RNAs. The structure of the 3' end of this viral RNA apparently resembles the structure of a tRNA and the last three bases of the viral RNA are...
The aaRSs are a set of cellular enzymes, each of which catalyzes the binding of an amino acid to its cognate tRNAs (formation of aminoacyl-tRNA) for incorporation into polypeptides, utilizing ATP. From: Autoantibodies (Second Edition), 2007 ...
导致其后所有的氨基酸序列发生改变，通常也会导致蛋白质失去功能；剪接位点的变异可能会影响RNA的正确剪接，...
【7】During translation, transfer RNA (tRNA) molecules, which are attached to a particular amino acid, will recognize a codon on the mRNA molecule and insert the appropriate amino acid at that location within the strand. 在翻译过程中,连接到特定氨...
An important impact of RNA editing is its ability to challenge the central dogma of biology. When RNA editing takes place in the coding sequence (CDS) region of an mRNA, where an I is recognized as a G or a C as a U after deamination, it can lead to amino acid substitutions (called...
核糖核酸(ribonucleic acid, RNA) 药物依赖中心法则和碱基互补配对原则, 在翻译水平特异且高效地调控靶标基因及相关下游通路, 产生治疗效果。自1998年全球首款RNA药物Fomivirsen获得美国食品药品监督管理局(Food and Drug Administration, FDA) 批准上市用于治疗巨细胞病毒性视网膜炎, 至2020年多款信使核糖核酸(messenger...
These interactions give rise to the secondary “cloverleaf” structure of tRNA; this base pairing results in three stem-loops and an open-ended stem formed by the pairing of the 5′ and 3′ ends. The latter stem is known as the acceptor stem, which binds an amino acid. Of the three ...
核糖核酸 (ribonucleic acid, RNA) 药物依赖中心法则和碱基互补配对原则,在翻译水平特异且高效地调控靶标基因及相关下游通路, 产生治疗效果。自1998年全球首款RNA 药物Fomivirsen 获得美国食品药品监督管理局 (food and drugadministration, FDA) 批准上市用于治疗巨细胞病毒性视网膜炎...
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