细胞穿透肽(cell penetrating peptide, CPP) 一般是由5~30个氨基酸组成的两亲性或阳离子肽片段, 包括HIV-1 (human immunodeficiency virus-1) 反式激活因子(HIV-Tat)、果蝇的触角足同源异形域的DNA结合结构域第3片段(peneytatin 1)、由神经肽甘丙肽和乳突蛋白合成的嵌合肽(transportan) 或基于碱性氨基酸(如精氨酸...
RNAlater Stabilization Solution stabilizes and protects cellular RNA in intact, unfrozen tissue samples, eliminating the need to immediately process tissue samples or to freeze samples in liquid nitrogen for later processing. In other words, it is an RNA preserving reagent. RNaseOUT Recombinant Ribonuc...
细胞穿透肽 (cell penetrating peptide, CPP) 一般是由5～30 个氨基酸组成的两亲性或阳离子肽片段, 包括HIV-1 (human immunodeficiency virus-1) 反式激活因子(HIV-Tat)、果蝇的触角足同源异形域的DNA 结合结构域第3 片段(peneytatin 1)、由神经肽甘丙肽和乳突蛋白合成的嵌合...
TYMV RNA as an Amino-acid DonorNo Abstract available for this article.doi:10.1038/241310b0NoneNature Publishing Group UKNature
【7】During translation, transfer RNA (tRNA) molecules, which are attached to a particular amino acid, will recognize a codon on the mRNA molecule and insert the appropriate amino acid at that location within the strand. 在翻译过程中,连接到特定氨...
The aaRSs are a set of cellular enzymes, each of which catalyzes the binding of an amino acid to its cognate tRNAs (formation of aminoacyl-tRNA) for incorporation into polypeptides, utilizing ATP. From: Autoantibodies (Second Edition), 2007 ...
TYMV RNA as an Amino-acid Donor THE single stranded genomic RNA of turnip yellow mosaic virus (TYMV) has some striking similarities to transfer RNAs. The structure of the 3' end of this viral RNA apparently resembles the structure of a tRNA and the last three bases of the viral RNA are...
例如，无义突变（nonsense mutation）会导致蛋白质合成提前终止，产生一个截短的、通常没有功能的蛋白质...
These interactions give rise to the secondary “cloverleaf” structure of tRNA; this base pairing results in three stem-loops and an open-ended stem formed by the pairing of the 5′ and 3′ ends. The latter stem is known as the acceptor stem, which binds an amino acid. Of the three ...
Poly(b-amino)esters (PBAEs) PBAE是一种单链,可降解的高分子聚合物,以伯胺或仲胺与二丙烯酸酯为原料合成,Chiellini于1983年首次报道PBAE [75]。MIT的Langer团队于2000年首次将PBAE用于DNA质粒递送 [76]。PBAE的胺基带正电,可与核酸中带负电的磷酸基团发生静电相互作用,形成高分子-核酸复合物。PBAE溶解性好,pK...