Splicing involves the precise removal of introns from pre-mRNA, such that exons are spliced together to form mature RNAs with intact translational reading frames. Splicing requires exon recognition, accurate cleavage and rejoining of exons.RNA splicingdepends on the proper recognition of exons guided ...
For mosteukaryoticgenes(and some prokaryotic ones), the initialRNAthat is transcribed from a gene'sDNAtemplate must be processed before it becomes a maturemessenger RNA(mRNA) that can direct thesynthesis ofprotein. One of the steps in this processing, called RNAsplicing, involves the removal or ...
Precursor messenger RNA (pre-mRNA) splicing is an essential step in the flow of information from DNA to protein in all eukaryotes. Research over the past four decades has molecularly delineated the splicing pathway, including characterization of the detailed splicing reaction, definition of the splice...
Background: RNA splicing is both ubiquitous and essential for the maturation of precursor mRNA molecules in eukaryotes. The process of trans-splicing involves the transfer of a short spliced leader (SL) RNA sequence to a consensus acceptor site on a separate pre-mRNA transcript. In Caenorhabditis...
Sex-specific alternative splicing of RNA from the Drosophila transformer gene involves competition between two 3′ splice sites. In the absence of Sex-lethal activity (as in males), only one site functions; in the presence of Sex-lethal activity (as in females), both sites function. Information...
Splicing of xtrRNA Splicing involves several regulated steps, many accessory factors and the spliceosome, a complex multi-component enzyme. There is currently a lack of mechanistic insight regarding how the splicing apparatus reacts when encountering pre-mRNA containing large repetitive sequence tracts [...
RNA editing and alternative splicing play an important role in expanding protein diversity and this is well illustrated in studies of nicotinic acetylcholine receptors (nAChRs). Here, we compare the RNA editing and alternative splicing of the nAChR alpha
In eukaryotes, in addition to mRNA, tRNA, and rRNA, there are “guide RNAs” used for post-translational editing of mRNA, RNA for incorporation into ribonucleoproteins involved in splicing eukaryotic mRNAs, and RNA for incorporation into certain transcription factors. In eukaryotes specialized RNA pol...
GENE expressionCELL motilityCOLON cancerBRAF genesOVERALL survivalRNA splicingThe initial step in pre-mRNA splicing involves formation of a spliceosome commitment... Y Zhang,AC Simko,U Okoro,... - 《Bioinformatics & Biology Insights》 被引量: 0发表: 2024年 加载更多来源...
Germ-line human £ heavy chain gene RNA transcripts utilize the full range of alternative 3' splicing seen in productive £ mRNA 来自 ResearchGate 喜欢 0 阅读量: 21 作者:K Zhang,LL Laboratory,D Diaz-Sanchez,AS* Hart 摘要: An early step in immunoglobulin isotype switching involves the ...