目前担任国际期刊Trends in genetics、Genome biology、Journal of Biological Chemistry编委。陈玲玲研究组从事长非编码RNA研究,近年来揭示细胞核内非编码RNA参与基因表达调控的机制(Genes Dev, 2015;Cell Res, 2014, 2015)。也首次创建非poly(A)转录组纯化体系(Gen
Together with the findings of circRNA binding PKR and sensitive to RNase L digestion, the study proposes a paradigm-shift model on how endogenous circRNAs may function to sponge abundant dsRNA-binding PKR in a cell to prevent PKR activation by endogenous dsRNA such as mitochondria-derived mtRNAs ...
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Cell Rep. 2019 Nov 12;29(7):1832-1847.e8. Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis ACD家族检测平台 聚研RNAscope实验室——为您提供RNA原位杂交检测服务(您只需提供切片...
These molecules function to process rRNA molecules, often resulting in the methylation and pseudouridylation of specific nucleosides. These modifications are mediated by one of two classes of snoRNAs: the C/D box or H/ACA box families, which generally mediate the addition of methyl groups or ...
Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function.[J] .Science, 2017, 357(6357). 6、Guarnerio Jlenia,Bezzi Marco,Jeong Jong Cheol et al. Oncogenic Role of Fusion-circRNAs Derived from Cancer-Associated Chromosomal Translocations.[J] .Cell, 2016, 165...