In recent years, cytoplasmic RNA granules, which are micron-sized membrane-less entities formed by phase separation, have progressively gained recognition as essential constituents of neuronal RNA metabolism. Stress granules form under adverse growth con
How the differences and similarities in the structures of DNA and RNA adapt them to their specific functions? What are three differences between DNA and RNA: Difference 1 - which sugar they use: DNA always uses (a sugar) and never uses the (a sugar) that RNA uses....
Learn the difference between DNA and RNA, learn about the 3 types of RNA and their functions and understand the structure and function of mRNA, tRNA and rRNA. Related to this Question Compare and contrast DNA and RNA in terms of structure and function. ...
SHP is an orphan nuclear receptor that contains the ligand-binding domain (LBD), but lacks the DNA binding domain (DBD) [73]. SHP functions as a transcriptional repressor though interacting with other NRs, and plays important roles in several metabolic diseases and in liver carcinogenesis [74–...
Non-coding RNAs (ncRNA) are essential for all life, and their functions often depend on their secondary (2D) and tertiary structure. Despite the abundance of software for the visualisation of ncRNAs, few automatically generate consistent and recognisable 2D layouts, which makes it challenging for ...
Another topic of intense research interest is that of microRNAs (miRNAs), which are small regulatory RNAs that are approximately 22 to 26 nucleotides in length. The existence of miRNAs and their functions ingene regulationwere initially discovered in thenematodeC. elegans(Leeet al., 1993; Wightman...
(miRNAs) and long non-coding RNAs (lncRNAs). Regarding function, m6A modification affects the processing, structure, splicing, localization, stability, degradation, and translation of RNAs and their functions, such as RNA–protein and RNA–RNA interactions.16,17,18The m5C can perform a similar ...
Guanine-rich sequences are able to form complex RNA structures termed RNA G-quadruplexes in vitro. Because of their high stability, RNA G-quadruplexes are proposed to exist in vivo and are suggested to be associated with important biological relevance. H
Notably, circRNAs display cell-type, tissue-type and developmental-stage specific expression patterns in eukaryotic transcriptome, which reveals their significant regulatory functions in gene expression. More importantly, circRNAs serve as microRNA (miRNA) sponges and crucial regulators of gene expression. ...
Long noncoding RNAs and their proposed functions in fibre development of cotton (Gossypium). The New Phytologist, 2015, 207(4): 1181-1197. [30] 闫飞林. 棉花纤维起始相关长链非编码 RNA 的功能鉴定[D]. 武汉: 华中农业大学, 2019. YAN F L. The functional identification of long non-coding RNA...