DNA pairs its bases with those of the "free" nucleotides (Figure 2). Messenger RNA (mRNA) then travels to the ribosomes in the cell cytoplasm, where protein synthesis occurs (Figure 3). The base triplets of transfer RNA (tRNA) pair with those of mRNA and at the same time deposit their...
we carried out a threshold-free statistical analysis based on the GSEA method37(see Methods). Importantly, we found the three distinct categories for both RBPs and functional units, with the M-RBP set being involved in a similar fraction of the significant functional...
Circular RNA (CircRNA) is a class of non-coding RNA with a closed ring structure, without 5’cap structure and 3’poly A tail, which makes them more resistant to digestion of RNase R and more stable than linear RNA. At the same time, they can resist the toxicity of actinomycin D. Cir...
a further step, it would be interesting to explore which pathways show involvement of PLPP6 and to what extent and under which conditions these pathways contribute to the pathogenesis of FM. In addition, studies of free circulating miRNAs during different phases of pain intensity could provide new...
rna-tools loves to be used with parallel (wirte in shell script what you want rna-tools to do) and run to execute it in a set of folders: parallel --bar --eta --progress 'cp test.sh {} && cd {} && bash test.sh ' ::: * ...
The symbols a is used generically to represent any nucleotide of RNA (a terminal symbol). All 16 possible base pairs are permitted, including non-canonical pairs with low probability. We can extend this grammar to the problem of pairwise structural alignment, the simultaneous sequence alignment ...
The RNA Seq-Atlas presented here provides a record of high-resolution gene expression in a set of fourteen diverse tissues. Hierarchical clustering of transcriptional profiles for these tissues suggests three clades with similar profiles: aerial, underground and seed tissues. We also investigate the re...
Small cell lung cancer (SCLC) is a highly lethal malignant tumor. It accounts for approximately 15% of newly diagnosed lung cancers. Long non-coding RNAs (lncRNAs) can regulate gene expression and contribute to tumorigenesis through interactions with mic
of promoter element arrangements. The tRNA genes (tDNAs) utilize what is referred to as a type 2 internal promoter, and the transcription factor binding sites within these genes are referred to as internal control regions (ICRs). Type 2 promoters contain conserved A-box and B-box ICR ...
What Is DNA? DNA stands for deoxyribonucleic acid. It's a macromolecule that is one of the most important components of our cells.Without DNA, cell functions like growth and reproduction wouldn't be possible. DNA Structure DNA is made up offour chemical bases: Adenine (A), Guanine (G), ...