Here, we investigated the hematotoxicity and recovery after comparable administered activities of [177Lu]Lu-PSMA-617 and [225Ac]Ac-PSMA-617 in RM1-PGLS mouse models. Methods: A total of n=25 mice were used in this study. Male C57BL/6 mice were inoculated subcutaneously with 0.1x106 RM1...
Here, we investigated the hematotoxicity and recovery after comparable administered activities of [177Lu]Lu-PSMA-617 and [225Ac]Ac-PSMA-617 in RM1-PGLS mouse models. Methods: A total of n=25 mice were used in this study. Male C57BL/6 mice were inoculated subcutaneously with 0.1x106 RM1...
This study investigated the hematotoxicity, treatment efficacy, and recovery after [ 177 Lu]Lu-PSMA-617 and [ 225 Ac]Ac-PSMA-617 treatment in a syngeneic PC mouse model.Twenty-five male C57BL/6 mice were inoculated with RM1-PGLS cells and monitored using [ 68 Ga]Ga-PSMA-11 PET/CT. ...