RM-1 cells are aggressive, non-immunogenic mouse prostate cancer cells that express very little MHC I, similar to many human prostate cancers. Our goal was to develop a whole cell tumor vaccine that would generate a protective T cell-dependent antitumor response.Grant, Julieann Francine...
进一步研究发现,荷瘤RM-1-B7-H3的C57BL/6小鼠肿瘤组织及脾脏组织中Gr-1+CD11b+MDSC细胞数量显著高于RM-1-mock荷瘤小鼠;同时,本论文还发现RM-1-B7-H3荷瘤小鼠体内MDSC凋亡率显著低于RM-1-mock荷瘤小鼠。 体外实验也证实RM-1-B7-H3细胞株与RM-1-mock细胞株相比,脾脏Gr-1+CD11b+MDSC凋亡率显著下降;人髓...
Thus, we present in this study a novel NKp46-lkdiated lkchanism of tumor editing.Although common evolutionary principles drive the growth of cancer cells regardless of the tissue of origin, the microenvironlknt in which tumours arise suaktantially diklers across various organ sites. Recent ...
Fig3. Detection of hPSMA expression on tumor cells in subcutaneous xenograft model of RM1-hPSMA cells (The tumors were collected at day 15 post tumor cell inoculation). 相关品系 MC38-hPSMA (2) 细胞系名称:MC38-Tg(hPSMA)Smoc 目录号:NM-S13-TM91 ...
5×106cells/瓶×2 SMC-1 (human pleural tumor cell) SMC-1(人胸膜瘤细胞) 5×106cells/瓶×2 SUP-B15 (human Ph+ acute lymphoblastic leukemia cell line) SUP-B15(人Ph+急淋细胞系) 小鼠细胞,RM-1细胞保存和应用:客户可以根据自己的需求选择新鲜或者冻存的原代细胞,如是新鲜原代细胞,客户收到细胞后...
Fig3. Detection of hPSMA expression on tumor cells in subcutaneous xenograft model of RM1-hPSMA cells (The tumors were collected at day 15 post tumor cell inoculation). 相关品系 MC38-hPSMA (2) 细胞系名称:MC38-Tg(hPSMA)Smoc 目录号:NM-S13-TM91 ...
Fukuoka University-Malignant mixed Mullerian Tumor-1细胞系相关产品:Hs600T细胞、NCI-SNU-182细胞、NRK clone 52E细胞 HPAF-2细胞系相关产品:L Wnt-3A细胞、NCI-H2107细胞、HMC3细胞 Experimental Mammary Tumour-6细胞系相关产品:TE 354.T细胞、bEND.3细胞、QGY7703细胞 ...
因此，有研究认为提高 CDK4 选择性抑制，可在降低 CDK6 相关毒性的同时改善CDK抑制剂的安全性和疗效。例如3月18日以CDK4 selective inhibition improves preclinical anti-tumor efficacy and safety为题发表于 Cancer Cell 期刊的一篇研究性论文。该研究先是探讨了肿瘤和造血系统中CDK4和CDK6的不同作用依赖性。通过...
20 and minor 15.5 kDa bands as a result of differential glycosylation. The biological activity of the IFN gamma homodimer is highly species specific. Human IFN gamma does not show cross-reactivity with mouse. IFN gamma function includes the following: antiviral activity, tumor antiproliferative activi...
20 and minor 15.5 kDa bands as a result of differential glycosylation. The biological activity of the IFN gamma homodimer is highly species specific. Human IFN gamma does not show cross-reactivity with mouse. IFN gamma function includes the following: antiviral activity, tumor antiproliferative activi...