Lymphomas and lymphoproliferations comprise 24% of posttransplant malignancies and Kaposi's sarcoma (KS) 6%, if non-melanoma skin cancers and in situ carcinomas of the uterine cervix are excluded, as they are from most studies of patterns of malignancy [1] . A gratifying feature is that ...
T-cell depletion of bone marrow for allogeneic transplantation is known to increase the risks of Epstein-Barr virus-driven lymphoproliferative disorders that may result in fatal lymphoma, especially with transplants from unrelated or mismatched donors. Over the past 15 years, we have...
Matched unrelated donor (MUD) bone marrow transplants have proven useful for many of these patients, however, matched donors may be unavailable or too time-consuming to find. In addition, MUD transplants are associated with high morbidity and mortality secondary to severe graft-versus-host disease...
That suggests that while these risks should be taken seriously, it’s still the case that CAR-T therapy’s benefits “for the vast majority of patients far outweigh the risks,” said David Porter, an oncologist at the University of Pennsylvania School of Medicine, who contributed to the first...
as are individuals whose immune system may not be working properly as a result of a known disease, or who are taking medications that suppress the immune system (for example, undergoing cancer treatment, a bone marrow or organ transplant, or suffering from immune deficiencies and/or autoimmune ...
Dr. Anna Fitch Courie, Director of Responder Wellness, FirstNet Program at AT&T is a nurse, Army wife, former university faculty, and author. Dr. Courie has worked for over 20 years in the health care profession including Bone Marrow Transplant, Intensive Care, Public Health, and Health Promo...
Among those affected by the contaminated syringes was Kyle Pacheco, a 19-year-old from South Florida who was recovering from a bone marrow transplant. According to ProPublica, Pacheco became so seriously ill from the contaminated syringe that he fell into a month-long coma and could barely walk...
in combination with bortezomib for the treatment of progressive multiple myeloma in patients who have received at least one prior therapy and who have already undergone or are unsuitable for bone marrow transplant; for treatment of AIDS-related Kaposi’s sarcoma (KS) in patients with low CD4 count...
Prospective validation of the predictive power of the hematopoietic cell transplantation comorbidity index: a Center for International Blood and Marrow Transplant Research study. Biol Blood Marrow Transplant. 2015;21(8):1479-1487.PubMedGoogle ScholarCrossref 28. Raimondi R, Tosetto A, Oneto R, ...
Researchers have begun using mesenchymal stem cell transplants to treat autoimmune diseases. It was thought that supplementing the body with a high amount of new stem cells would boost a patient’s ability to fight inflammation and reduce symptoms caused by autoimmune disorders. Mesenchymal stem cells...