Risk Group 4 pathogens are a group of often lethal human viruses for which there are no widely available vaccines or therapeutics. These viruses are endemic to specific geographic locations and typically cause relatively infrequent, self-limiting, but often devastating human disease outbreaks (e.g. ...
Introduction: The development of therapeutics and vaccines to combat Risk Group 4 pathogens, which are associated with high case-fatality rates, is a high priority. Post-exposure prophylactic vaccines have the potential to bridge classical therapeutic and vaccine applications, but little progress has ...
Mahieux R, Gessain A (2011) HTLV-3/STLV-3 and HTLV-4 Viruses: Discovery, Epidemiology, Serology and Molecular Aspects Viruses. 2011 July; 3(7):1074–1090. doi:10.3390/v3071074 Google Scholar Maillard JC, Gonzalez JP (2006) Biodiversity and emerging diseases. Ann N Y Acad Sci 1081:1–...
Genome-wide association studies (GWAS) have identified 233 commonly occurring genetic variants that are associated with MS; 32 variants are located in the human leukocyte antigen (HLA) region and 201 are located outside the HLA region4. The strongest MS associations are found in the HLA region,...
and the NEC Group could also be liable for recall costs. In particular, although products and services generally related to ICT solutions are exposed to customary risks of technology failure or computer viruses, many of the NEC Group’s products and services are used in infrastructure that is di...
Plants on which we depend for food are under attack from insects, fungi, bacteria, viruses, rodents and other animals, and must compete with weeds for nutrients. To kill unwanted populations living in or on their crops, farmers use pesticides. The first widespread insecticide use began at the...
Top motivators of cyber-attacks Malicious files can be delivered as email attachments, which can contain viruses, ransomware, or other malware. Clicking a link in a suspicious email can redirect the user to a malicious website that can download malware or steal personal information. One of the...
occurrence of cancers of the liver, oral cavity/pharynx, and non-Hodgkin lymphoma may reflect underlying immunosuppression, possible role of herpesvirus 8, and behavioral factors that increase chances of viral infection (eg, human immunodeficiency virus, human papillomavirus, hepatitis viruses B and C)...
"ivermectin's key direct target in mammalian cells is a not a viral component, but a host protein important in intracellular transport; the fact that it is a host-directed agent (HDA) is almost certainly the basis of its broad-spectrum activity against a number of different RNA viruses in ...
Kandil ME, Rasheed MA, Saad NE: Hepatitis C and B viruses among some high risk groups of Egyptian children. J Med Sci 2007, 7 (8) : 1259-1267.Hepatitis C and B Viruses Among Some High Risk Groups of Egyptian Children. Manal E. Kandil,Maha A. Rasheed,Nevine E. Saad. Journal of ...