database of 457,331 participants aged 50 to 71 years and examined the association between weight status and the incidence rate of PTC. All subjects were asked to complete a self-report questionnaire on health, lifestyle, and BMI. The resulting analysis showed that the risk for PTC was ...
For studies reporting rate ratios, those were converted to ORs using the methods defined in the Cochrane Handbook for Systematic Reviews of Interventions.14 Summary statistics were expressed as ORs and 95% CIs. Prediction intervals were also reported. Statistical heterogeneity was assessed using the I...
Objective To evaluate the rate of within-couple HIV transmission (heterosexual and men who have sex with men [MSM]) during periods of sex without condoms and when the HIV-positive partner had HIV-1 RNA load less than 200 copies/mL. Design, Setting, and Participants The prospective, observatio...
There is insufficient scientific evidence for the participation rate in physical training as a modifiable risk factor. Physical training: personnel, non-military training (high amounts) Eight studies focused on high amounts of training during free time (non-military training) as a risk factor for ...
did not align with the gender documented in phenotype data. Variants were excluded if the call-rate was below 95% or if the HWE p-value was less than 1e-4 (only autosomal variants). In addition, SNPs that showed potential traces of batch bias were removed. Two batch bias control steps...
The difference in mutation prevalence could be influenced by the selection of the patients included; indeed, studies including only HPCa patients report a lower mutation rate than studies including HPCa families. We also identified a family that had DM in both BRCA1 and BRCA2 genes, with a ...
samples were jointly called. Markers passing all the QC tests were used in downstream analysis (NSNPs = 729,868; 95.4%) using the SNPolisher R package (Thermo Fisher). To assess the sample genotyping concordance, we intentionally resampled 200 samples and determined a concordance rate of ...
German NoV surveillance data re- ported similar NoV-associated mortality rate estimates per 10,000 namely, <0.01 in those <70 years to approxi- mately 0.32 among those ≥70 years [63]. Dutch model-based estimates suggest that seasonal vi- ruses account for nearly 5 % of all-cause ...
Postoperatively, length of stay, occurrence of complications, in-hospital mortality, overall survival, and disease-free survival were recorded. Patients who underwent gastrectomy in palliative intention were excluded from analysis. Furthermore, patients who died during their stay in hospital (= in-hospi...
A high-risk late gadolinium enhancement (LGE) pattern was defined as epicardial, transmural, or septal plus free-wall. The primary outcome was a composite of heart failure hospitalizations and all-cause mortality. Multivariable analyses were performed to evaluate the impact of DM on outcomes. ...