Methods: Numerous electronic databases were systematically searched to identify patient-specific risk factors and clinical characteristics of EDKA in patients on SGLT-2i. The patient's symptoms, clinical profile, laboratory results, and precipitants for EDKA were reviewed. Results: A total of 96 ...
A second step for DKA prevention is directly addressing modifiable risk factors via diabetes self-management education, and medical and psychological interventions (figure 1). A promising strategy to address several modifiable risk factors simultaneously is diabetes self-management education, which has been...
We suggest several factors that may be responsible for driving this inertia; each will need to be addressed if we are to ensure that eligible, at-risk patients are to benefit from the risk reductions proven in CVOTs, and now emerging from dedicated HF and renal studies Full size image It ...
Drivers of clinical inertia in the management of cardiorenal risk in T2D. We argue that the slow uptake of SGLT2i and GLP-1 RA following CVOT disclosures can be attributed to clinical inertia. We suggest several factors that may be responsible for driving this inertia; each will need to be ...
The clinical presentation of SGLT2 inhibitor-induced diabetic ketoacidosis (DKA) can be subtle, and patients may not necessarily exhibit hyperglycemia. Diagnosis can be complicated by other comorbidities, precipitating factors, and concurrent medications. Additionally, primary care clinicians may lack the ...
This is especially important in patients who have risk factors for diabetes such as a high body mass index (BMI), physical inactivity, a family history of diabetes, and history of gestational diabetes, or those who will be treated with targeted agents that are associated with hyperglycemia. ...
The goal of the study was to identify the novel metabolic indices with high predictive power and can also be combine with the conventional risk factors to develop a machine learning model that can identify individuals at risk of developing chronic kidney disease earlier and precisely at low cost ...
While numerous factors contribute to gut barrier dysfunction, a Western diet has been implicated [6]. In particular, poor diet quality drives hyperglycemia [7], which damages tight junctions of the intestinal epithelium resulting in ‘leaky gut’ [8]. Thus, nutrition strategies that improve gut ...
Cold-pressed chia seed oils (ChO) are known for their health-promoting characteristics due to their high content of omega-3 α-linolenic acid (ω-3 ALA). We investigated the influence of ChO supplementation as a functional food on animal models of the cardiovascular risk factors hypercholesterolem...