COVID-19-related worries Worries in relation to COVID-19 were assessed with 8 slider-items from 0.0–10.0, with higher values indicating more worries (Supplementary Table S1). We conducted a factor analysis (FA) and principal component analysis (PCA) to identify the latent factors underlying th...
RNA-seq data from patient-derived samples of three diseases (multiple sclerosis, lupus and CAD) were used to calculate the overall editing levels of dsRNAs associated with risk vs protective alleles and the IFN scores. We used allele-specific editing analysis to determine editing levels associated ...
The pooled 1-year absolute risk of completed suicide increased by a factor of 0.16 (95% CI, 0.01-0.32) for every percentage increase in male sex in the study cohort. The pooled 1-year absolute risk of completed suicide was lower in retrospective studies than prospective studies (−3.57;...
Single-factor analysis and multiple-factor regression analysis were used to analyze potential risk factors of cognitive impairment. Results Mini-Mental State Examination test results showed that 22 patients had cognitive impairment, and MoCA test results showed that 10 patients had cognitive impairment. ...
What are the potential implications for the instrumentalization of alcohol use? In short, the functionality gains of alcohol use need to be weighed against the potential risks. This weighting will crucially depend on the life cycle. Globally, alcohol is the most important risk factor for death an...
In post hoc analysis of the Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation–Thrombolysis in Myocardial Infarction 48 trial,36 findings suggested that edoxaban vs warfarin lowered fracture risk (HR, 0.88; 95% CI, 0.75-1.03) among participants at increased risk of ...
We included 46 factors on the basis: (1) a potentially modifiable risk factor, (2) publicly available genome-wide association studies (GWASs) or summary level data, (3) the number of instrument variables (IVs) ≥ 3. To assess the causal relationships of modifiable risk factors with ...
Consumption of peppers was significantly associated as having a protective effect for SE PT8 cases when compared to the non-PT8/non-PT13a cases. This result could also indicate that consuming peppers is a risk factor for SE infections with the non-PT8/non-PT13a cases. Historically foodborne ...
protective factors in family and school environments and depressive symptoms. Association rule mining, a machine learning method, was used in the data analyses to identify the correlation between risk/protective factor combinations and depression. We found that (1) Family cohesion, family conflict, ...
Additionally, SSRIs reduce growth hormone and insulin-like growth factor (IGF) levels, and IGF participates in progression of BE to EAC, based on immunohistochemical analysis of human BE, LGD, HGD and EAC25. Either of these mechanisms could potentially account for the protective effect of SSRIs...