Low folate and elevated tHcy levels are risk factors for neural tube defects (NTD). Therefore, we examined whether this polymorphism is associated with NTD risk and plasma folate, erythrocyte folate and plasma tHcy levels in 96 NTD patients, 113 mothers, 97 fathers and 101 controls. This ...
(7), in which we set the proportion of the risk SNPs to π = 0.05 and the variance of the risk effects to σ2 = 0.001n. Here n is the total sample size of the GWAS used in the training data. We assume the GWAS is balanced with an equal number of cases and controls....
et al. Cigarette smoking, tar yields, and non-fatal myocardial infarction: 14,000 cases and 32,000 controls in the United Kingdom. The International Studies of Infarct Survival (ISIS) Collaborators. BMJ 311, 471–477 (1995). Article CAS PubMed PubMed Central Google Scholar US Department of...
423 cataract patients and 608 controls between the ages of 50 and 79 were interviewed in a case-control study in Oxfordshire. Diabetes, myopia, glaucoma, peripheral neuropathy and severe diarrhoea were identified as risk factors. The excess risk experienced by females with diabetes was confirmed. ...
To examine the importance of risk factors for falls in the epidemiology of hip fracture, we performed a case-control study of 174 women (median age, 80 years) admitted with a first hip fracture to 1 of 30 hospitals in New York and Philadelphia. Controls, matched to the case patients ...
Conversely, HDL-C and apoA-I concentrations were significantly lower in coronary artery disease patients than in controls. Table 1. Clinical and biochemical characteristics of the study population. CharacteristicsCoronary artery disease patients (n = 212) Mean ± SD or n (%)Controls (n = 104) ...
“Biologic markers in ethylene exposed workers and controls”. Mutation Research 1991; 248:163–176. Article CAS Google Scholar McCann J, Coi E, Yamasaki E and Ames BN. “Detection of carcinogens as mutagens in the Salmonella / microsome test: assay of 300 chemicals” — Proc. Nat. Acad....
the pooled OR of enteric infections in ASD users was 2.55, with a greater association for PPIs (OR 3.33) compared to H2RAs (OR 2.03) [121]. Similarly, a recent nested case–control study of a national database on hospitalised population (14,736 case patients and 58,944 controls) report...
Maternal smoking in pregnancy and birth defects: a systematic review based on 173 687 malformed cases and 11.7 million controls. Hum. Reprod. Update 17, 589–604 (2011). Article CAS PubMed PubMed Central Google Scholar Thorup, J., Cortes, D. & Petersen, B. L. The incidence of ...
Sample size in FINRISK (CHD, n = 20,165; AF, n = 21,030; T2D n = 10,561) and in FinnGen (breast cancer, n = 37,841; prostate cancer n = 48,851), using respective incident disease cases and controls. Correlation was assessed with Pearson correlation. Extended Data Fig. 6 ...