Right heart failure most commonly results from the complication of left heart failure (systolic or nonsystolic dysfunction) or pulmonary hypertension. Over the past decade, greater attention has been paid to the role of right ventricular failure in the morbidity and mortality associated with cardiomyopa...
Pathophysiology of impaired right and left ventricular function in chronic embolic pulmonary hypertension: Changes after pulmonary thromboendarterectomy. Chest. 2000;118:897-903Menzel T, Wagner S, Kramm T, Mohr-Kahaly S, Mayer E, Braeuninger S, et al. Pathophysiology of impaired right and left ...
47. Guazzi M, Villani S, Generati G, et al. Right ventricular contractile reserve and pulmonary circulation uncoupling during exercise challenge in heart failure: pathophysiology and clinical phenotypes. JACC Heart Fail 2016;4:625-635. 48. Sharma T, Lau EMT, Choudhary P, et al. Dobutamine s...
Due to current scope of heart failure (HF) epidemics, exploration of new approaches to prevent or stabilize HF is a priority for research. One of important milestones of HF progression is the onset of right ventricular failure due to transition of initially left ventricular disease into biventricu...
Use of serum fibroblast growth factor 23 vs. plasma B-type natriuretic peptide levels in assessing the pathophysiology of patients with heart failure. Hypertens Res 2017; 40: 181–188. 2 Larsson T, Nisbeth U, Ljunggren O, Jüppner H, Jonsson KB. Circulating concentration of FGF-23 increases...
In children with large left-to-right shunts secondary to congenital heart defects the imbalance between the pulmonary and systemic perfusion may lead to circulatory congestion with clinical signs similar to those of heart failure. The circulatory function in this state was evaluated by using the invas...
Heart failure therapies used in acquired left heart failure are often initiated in adults with right heart failure due to congenital heart disease, but the right ventricle differs substantially from the left ventricle, and the clinical evidence for this treatment strategy is lacking. In this review,...
The RV wall is thinner and more compliant than the left ventricle (LV)6 and its stroke work is a quarter that of the LV despite similar stroke volumes7. To date, the advances made in cardiac magnetic resonance imaging (MRI) enabled acquisition of high-resolution images of the heart8 for ...
Circulatory failure due to left-to-right shunts in children with congenital heart disease - Pathophysiology and therapeutic consequences Pediatric Research publishes original papers, invited reviews, and commentaries on the etiologies of diseases of children and disorders of development, extending from molecu...
1 This document, however, focused on the left heart, with only a small section covering the right-sided chambers. Since this publication, there have been significant advances in the echocardiographic assessment of the right heart. In addition, there is a need for greater dissemination of details...