RIG-I-like receptor signaling pathway Specific families of pattern recognition receptors are responsible for detecting viral pathogens and generating innate immune responses. Non-self RNA appearing in a cell as a result of intracellular viral replication is recognized by a family of cytosolic RNA helica...
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2017. Negative regulators of the RIG-I-like receptor signaling pathway. Eur J Immunol 47:615- 628. https://doi.org/10.1002/eji.201646484.Quicke KM, Diamond MS, Suthar MS. Negative regulators of the RIG-I-like receptor signaling pathway. Eur J Immunol. 2017;47:615-28....
RNA,activate the RIG-I signaling pathway,promote the production of cytokines and exert the antiviral effect.This study reviews the various signaling pathways and regulatory mechanisms of RIG-I like receptors,providing new ideas and directions for the control of viral infection and immunomodulatory ...
HSCARG Negatively Regulates the Cellular Antiviral RIG-I Like Receptor Signaling Pathway by Inhibiting TRAF3 Ubiquitination via Recruiting OTUB1. Yanyan Peng,Ruidan Xu,Xiaofeng Zheng. PLoS Pathog . 2014Peng, Y.; Xu, R.; Zheng, X. HSCARG negatively regulates the cellular antiviral RIG-I like ...