A ribosome is one of the smallest structures in a cell, but it has a very big job: to make protein. A ribosome is an organelle. Organelles are like tiny factories that help the cells of plants and animals function properly. Organelles are found in the cytoplasm of the cell. Cytoplasm ...
However, the function of Def has not been characterized in the mammalian digestive organs. In this report, we show that conditional knockout of the mouse def gene in hepatocytes causes cell morphology abnormality and constant infiltration of inflammatory cells in the liver. As age increases, the ...
US researchers have used NMR to uncover the mechanism of ribosomal activity and to help explain why this ubiquitous piece of cellular machinery is so effective at its job. The ribosome is an organelle found in the cytoplasm of the living cell. It is composed of proteins and RNA and carries ...
Cells have little compartments called organelles. Each organelle does a specific job for the cell. The cell membrane, cytoplasm, and ribosomes are examples of organelles that all cells have. Ribosomes: Ribosomes are present in all cells, and are found either in the cytoplasm, or bound to the...
Wiley Job NetworkThe quantitative interaction of [G- 3 H]gougerotin with Escherichia coli and Saccharomyces cerevisiae ribosomes is studied in this contribution. While E. coli ribosomes show an homogeneous single-site interaction with the antibiotic (dissociation constant = 1.5 渭M), S. cerevisiae...
Wiley Job Networkdoi:10.1042/BC20090141cellmigrationfocaladhesionlocalizationribosometalintranslationinitiationfactorBackground information. The spatial localization of translation can facilitate the enrichment of proteins at their sites of function while also ensuring that proteins are expressed in the proximity ...
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Mol. Cell. Neurosci. 2, 305–314 (1991). Article CAS Google Scholar Weiler, I. J. & Greenough, W. T. Metabotropic glutamate receptors trigger postsynaptic protein synthesis. Proc. Natl Acad. Sci. USA 90, 7168–7171 (1993). Article CAS ADS Google Scholar Job, C. & Eberwine, J. ...
I was convinced that the ribosome phase problem was soluble. Cryo-EM structures might do the job. Molecular replacement is a computational method for using the structure of one macromolecule to estimate the phases of the reflections in the diffraction pattern produced by a crystal of another macrom...
Therefore, we conclude that Sra- and RimJ-mediated ribosomal function is required for precise timing of initiation of chromosome replication.doi:10.1002/jobm.201800295Zhang ShujunWunier WunierYao YuanMorigen MorigenJournal of Basic Microbiology